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          System Message

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          LOADING ...
          See other NOD2 SIRNA Assays ›
          Gene Symbol:
          Nod2
          Gene Name:
          nucleotide-binding oligomerization domain containing 2
          Gene Aliases:
          ACUG, BLAU, CD, Card15, F830032C23Rik, IBD1, Nlrc2
          Chromosome Location:
          Chr.8: 88647280 - 88688474 on Build GRCm38
          UniGene ID:
          Mm.222633
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID 90247

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 4,126.00
          Your Price
          Online offer:
          4126.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Nod2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_145857.2 NP_665856.2 2 331
          GenBank mRNA AF520774.1 - 2 376
          AK089390.1 - 2 295
          AK089843.1 - 2 295
          AY160220.1 - 1 260
          AY160221.1 - 2 332
          BC044774.2 - 2 292

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          More Information


          Panther Classification:

          Molecular Function -

          non-motor microtubule binding protein scaffold/adaptor protein

          Gene Ontology Categories:

          Function(s) Process(es)

          innate immune response in mucosa
          activation of immune response
          cytokine production involved in immune response
          cytokine secretion involved in immune response
          immune system process
          immunoglobulin production involved in immunoglobulin mediated immune response
          positive regulation of dendritic cell antigen processing and presentation
          negative regulation of T cell mediated immunity
          positive regulation of dendritic cell cytokine production
          positive regulation of type 2 immune response
          negative regulation of inflammatory response to antigenic stimulus
          positive regulation of humoral immune response mediated by circulating immunoglobulin
          defense response
          inflammatory response
          positive regulation of antibacterial peptide biosynthetic process
          positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria
          signal transduction
          positive regulation of cell proliferation
          detection of biotic stimulus
          detection of bacterium
          maintenance of gastrointestinal epithelium
          positive regulation of protein ubiquitination
          negative regulation of NF-kappaB transcription factor activity
          response to peptidoglycan
          response to muramyl dipeptide
          response to lipopolysaccharide
          detection of muramyl dipeptide
          negative regulation of interferon-gamma production
          negative regulation of interleukin-12 production
          negative regulation of interleukin-18 production
          negative regulation of interleukin-2 production
          negative regulation of tumor necrosis factor production
          positive regulation of interleukin-1 beta production
          positive regulation of interleukin-10 production
          positive regulation of interleukin-12 production
          positive regulation of interleukin-17 production
          positive regulation of interleukin-6 production
          positive regulation of tumor necrosis factor production
          positive regulation of stress-activated MAPK cascade
          negative regulation of toll-like receptor 2 signaling pathway
          activation of MAPK activity involved in innate immune response
          intracellular signal transduction
          defense response to bacterium
          regulation of apoptotic process
          positive regulation of I-kappaB kinase/NF-kappaB signaling
          response to exogenous dsRNA
          positive regulation of MAPK cascade
          positive regulation of phosphatidylinositol 3-kinase activity
          negative regulation of growth of symbiont in host
          innate immune response
          positive regulation of innate immune response
          positive regulation of Notch signaling pathway
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of JNK cascade
          positive regulation of epithelial cell proliferation
          positive regulation of interleukin-1 beta secretion
          regulation of inflammatory response
          positive regulation of peptidyl-tyrosine phosphorylation
          positive regulation of phagocytosis
          defense response to Gram-positive bacterium
          positive regulation of B cell activation
          positive regulation of NF-kappaB transcription factor activity
          protein oligomerization
          positive regulation of oxidoreductase activity
          positive regulation of nitric-oxide synthase biosynthetic process
          positive regulation of prostaglandin-endoperoxide synthase activity
          positive regulation of ERK1 and ERK2 cascade
          nucleotide-binding oligomerization domain containing 2 signaling pathway
          cellular response to peptidoglycan
          cellular response to muramyl dipeptide
          macrophage inflammatory protein-1 alpha production
          regulation of neutrophil chemotaxis
          positive regulation of cytokine production involved in inflammatory response
          negative regulation of macrophage apoptotic process
          positive regulation of prostaglandin-E synthase activity
          nucleotide binding
          protein binding
          ATP binding
          endodeoxyribonuclease activity, producing 5'-phosphomonoesters
          enzyme binding
          protein kinase binding
          muramyl dipeptide binding
          peptidoglycan binding
          CARD domain binding

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