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          System Message

          OKCancel
          LOADING ...
          See other CASP8 SIRNA Assays ›
          Gene Symbol:
          CASP8
          Gene Name:
          caspase 8
          Gene Aliases:
          ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5
          Chromosome Location:
          Chr.2: 201233443 - 201287711 on Build GRCh38
          UniGene ID:
          Hs.599762
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 9572

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 4,126.00
          Your Price
          Online offer:
          4126.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: CASP8
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001080124.1 NP_001073593.1 3 360
          NM_001080125.1 NP_001073594.1 2 503
          NM_001228.4 NP_001219.2 3 428
          NM_033355.3 NP_203519.1 3 334
          NM_033356.3 NP_203520.1 2 265
          NM_033358.3 NP_203522.1 3 428
          NR_111983.1 2 503
          XM_005246885.1 XP_005246942.1 2 323
          XM_005246886.1 XP_005246943.1 2 249
          XM_005246887.1 XP_005246944.1 3 401
          XM_005246888.1 XP_005246945.1 3 343
          XM_005246889.1 XP_005246946.1 2 220
          XM_005246890.3 XP_005246947.1 2 227
          XM_005246891.4 XP_005246948.1 2 467
          XM_005246892.1 XP_005246949.1 2 220
          XM_005246893.2 XP_005246950.1 2 323
          XM_005246894.3 XP_005246951.1 3 398
          XM_005246895.2 XP_005246952.1 2 323
          XM_006712789.1 XP_006712852.1 3 360
          XM_006712790.3 XP_006712853.1 2 239
          XM_006712793.2 XP_006712856.1 3 401
          GenBank mRNA AA312258.1 - 2 246
          AB451282.1 - 1 125
          AB451414.1 - 1 125
          AF009620.1 - 1 125
          AF380342.1 - 2 210
          AF422926.1 - 2 260
          AF422927.1 - 3 348
          AF422928.1 - 3 322
          AF422929.1 - 2 390
          AK310630.1 - 3 401
          AL601594.1 - 2 266
          BC028223.2 - 1 152
          BC068050.1 - 2 215 6421760
          BX395849.2 - 2 214
          CB990598.1 - 3 345
          DA420056.1 - 3 362
          EU168332.1 - 1 125
          EU670044.1 - 1 125
          JN657192.1 - 1 87
          U58143.1 - 1 125
          U60520.1 - 3 381
          X98172.1 - 2 416
          X98173.1 - 2 197
          X98176.1 - 3 314
          X98177.1 - 1 125
          X98178.1 - 1 125

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          More Information


          Panther Classification:

          Molecular Function -

          protease

          Gene Ontology Categories:

          Function(s) Process(es)

          proteolysis
          apoptotic process
          activation of cysteine-type endopeptidase activity involved in apoptotic process
          cellular component disassembly involved in execution phase of apoptosis
          cell surface receptor signaling pathway
          response to cold
          regulation of tumor necrosis factor-mediated signaling pathway
          regulation of necrotic cell death
          natural killer cell activation
          macrophage differentiation
          response to cobalt ion
          response to estradiol
          response to lipopolysaccharide
          response to tumor necrosis factor
          TRIF-dependent toll-like receptor signaling pathway
          TRAIL-activated apoptotic signaling pathway
          suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process
          T cell activation
          B cell activation
          positive regulation of I-kappaB kinase/NF-kappaB signaling
          negative regulation of I-kappaB kinase/NF-kappaB signaling
          response to ethanol
          positive regulation of macrophage differentiation
          positive regulation of proteolysis
          response to antibiotic
          protein heterooligomerization
          proteolysis involved in cellular protein catabolic process
          syncytiotrophoblast cell differentiation involved in labyrinthine layer development
          nucleotide-binding oligomerization domain containing signaling pathway
          cellular response to mechanical stimulus
          cellular response to organic cyclic compound
          death-inducing signaling complex assembly
          apoptotic signaling pathway
          extrinsic apoptotic signaling pathway
          execution phase of apoptosis
          activation of cysteine-type endopeptidase activity
          activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
          positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
          regulation of extrinsic apoptotic signaling pathway via death domain receptors
          negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
          cysteine-type endopeptidase activity
          death receptor binding
          tumor necrosis factor receptor binding
          protein binding
          peptidase activity
          cysteine-type peptidase activity
          ubiquitin protein ligase binding
          protein complex binding
          death effector domain binding
          identical protein binding
          scaffold protein binding
          cysteine-type endopeptidase activity involved in apoptotic process
          cysteine-type endopeptidase activity involved in apoptotic signaling pathway

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