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          System Message

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          LOADING ...
          See other CASP8 SIRNA Assays ›
          Gene Symbol:
          CASP8
          Gene Name:
          caspase 8
          Gene Aliases:
          ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5
          Chromosome Location:
          Chr.2: 201233443 - 201287711 on Build GRCh38
          UniGene ID:
          Hs.599762
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID HSS141460
          Size 20 nmol
          Availability Made To Order
          Catalog # 1299001
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: CASP8
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001080124.1 NP_001073593.1 3 322
          NM_001080125.1 NP_001073594.1 2 465
          NM_001228.4 NP_001219.2 3 390
          NM_033355.3 NP_203519.1 3 296
          NM_033356.3 NP_203520.1 2 227
          NM_033358.3 NP_203522.1 3 390
          NR_111983.1 2 465
          XM_005246885.1 XP_005246942.1 2 285
          XM_005246886.1 XP_005246943.1 2 211
          XM_005246887.1 XP_005246944.1 3 363
          XM_005246888.1 XP_005246945.1 3 305
          XM_005246889.1 XP_005246946.1 2 182
          XM_005246890.3 XP_005246947.1 2 189
          XM_005246891.4 XP_005246948.1 2 429
          XM_005246892.1 XP_005246949.1 2 182
          XM_005246893.2 XP_005246950.1 2 285
          XM_005246894.3 XP_005246951.1 3 360
          XM_005246895.2 XP_005246952.1 2 285
          XM_006712789.1 XP_006712852.1 3 322
          XM_006712790.3 XP_006712853.1 2 201
          XM_006712793.2 XP_006712856.1 3 363
          GenBank mRNA AA312258.1 - 2 208
          AB451282.1 - 1 87
          AB451414.1 - 1 87
          AF009620.1 - 1 87
          AF380342.1 - 2 172
          AF422926.1 - 2 222
          AF422927.1 - 3 310
          AF422928.1 - 3 284
          AF422929.1 - 2 352
          AK310630.1 - 3 363
          AL600571.1 - 2 460
          AL601594.1 - 2 228
          BC028223.2 - 1 114
          BC068050.1 - 2 177 6421760
          BX395849.2 - 2 176
          CB990598.1 - 3 307
          DA420056.1 - 3 324
          EU168332.1 - 1 87
          EU670044.1 - 1 87
          JN657192.1 - 1 49
          U58143.1 - 1 87
          U60520.1 - 3 343
          X98172.1 - 2 378
          X98173.1 - 2 159
          X98176.1 - 3 276
          X98177.1 - 1 87
          X98178.1 - 1 87

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          More Information


          Panther Classification:

          Molecular Function -

          protease

          Gene Ontology Categories:

          Function(s) Process(es)

          proteolysis
          apoptotic process
          activation of cysteine-type endopeptidase activity involved in apoptotic process
          cellular component disassembly involved in execution phase of apoptosis
          cell surface receptor signaling pathway
          response to cold
          regulation of tumor necrosis factor-mediated signaling pathway
          regulation of necrotic cell death
          natural killer cell activation
          macrophage differentiation
          response to cobalt ion
          response to estradiol
          response to lipopolysaccharide
          response to tumor necrosis factor
          TRIF-dependent toll-like receptor signaling pathway
          TRAIL-activated apoptotic signaling pathway
          suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process
          T cell activation
          B cell activation
          positive regulation of I-kappaB kinase/NF-kappaB signaling
          negative regulation of I-kappaB kinase/NF-kappaB signaling
          response to ethanol
          positive regulation of macrophage differentiation
          positive regulation of proteolysis
          response to antibiotic
          protein heterooligomerization
          proteolysis involved in cellular protein catabolic process
          syncytiotrophoblast cell differentiation involved in labyrinthine layer development
          nucleotide-binding oligomerization domain containing signaling pathway
          cellular response to mechanical stimulus
          cellular response to organic cyclic compound
          death-inducing signaling complex assembly
          apoptotic signaling pathway
          extrinsic apoptotic signaling pathway
          execution phase of apoptosis
          activation of cysteine-type endopeptidase activity
          activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
          positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
          regulation of extrinsic apoptotic signaling pathway via death domain receptors
          negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
          cysteine-type endopeptidase activity
          death receptor binding
          tumor necrosis factor receptor binding
          protein binding
          peptidase activity
          cysteine-type peptidase activity
          ubiquitin protein ligase binding
          protein complex binding
          death effector domain binding
          identical protein binding
          scaffold protein binding
          cysteine-type endopeptidase activity involved in apoptotic process
          cysteine-type endopeptidase activity involved in apoptotic signaling pathway

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