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          System Message

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          LOADING ...
          See other PDGFB SIRNA Assays ›
          Gene Symbol:
          PDGFB
          Gene Name:
          platelet derived growth factor subunit B
          Gene Aliases:
          IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis
          Chromosome Location:
          Chr.22: 39223359 - 39245055 on Build GRCh38
          UniGene ID:
          Hs.1976
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID HSS143262
          Size 20 nmol
          Availability Made To Order
          Catalog # 1299001
          Price Contact Us
          Your Price
          Online offer:
          3062.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: PDGFB
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_002608.3 NP_002599.1 5 1573
          NM_033016.3 NP_148937.1 5 473
          GenBank mRNA BC029822.1 - 5 793 5174750
          BC077725.1 - 5 1305 6379783
          CR456538.1 - 5 489
          CR541807.1 - 5 481
          M12783.1 - 5 1573
          X02744.1 - 5 598
          X02811.1 - 5 1463
          X03702.1 - 4 406
          X83705.1 - 5 473

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          More Information


          Panther Classification:

          Molecular Function -

          growth factor

          Gene Ontology Categories:

          Function(s) Process(es)

          MAPK cascade
          response to hypoxia
          embryonic placenta development
          positive regulation of endothelial cell proliferation
          monocyte chemotaxis
          platelet degranulation
          positive regulation of glomerular filtration
          DNA replication
          protein phosphorylation
          transforming growth factor beta receptor signaling pathway
          heart development
          positive regulation of cell proliferation
          response to wounding
          negative regulation of phosphatidylinositol biosynthetic process
          negative regulation of platelet activation
          positive regulation of gene expression
          negative regulation of gene expression
          regulation of phosphatidylinositol 3-kinase signaling
          positive regulation of phosphatidylinositol 3-kinase signaling
          positive regulation of smooth muscle cell migration
          cell growth
          peptidyl-serine phosphorylation
          peptidyl-tyrosine phosphorylation
          hemopoiesis
          extracellular matrix organization
          positive regulation of cell migration
          positive regulation of protein autophosphorylation
          negative regulation of protein binding
          activation of protein kinase activity
          activation of protein kinase B activity
          response to estradiol
          response to insulin
          positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
          paracrine signaling
          wound healing
          response to drug
          positive regulation of MAP kinase activity
          positive regulation of MAPK cascade
          positive regulation of blood vessel endothelial cell migration
          positive regulation of GTPase activity
          positive regulation of phosphatidylinositol 3-kinase activity
          response to estrogen
          positive regulation of cyclin-dependent protein serine/threonine kinase activity
          positive regulation of DNA replication
          positive regulation of mitotic nuclear division
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          phosphatidylinositol phosphorylation
          platelet-derived growth factor receptor signaling pathway
          phosphatidylinositol-mediated signaling
          positive regulation of fibroblast proliferation
          positive regulation of smooth muscle cell proliferation
          positive regulation of peptidyl-tyrosine phosphorylation
          positive chemotaxis
          positive regulation of chemotaxis
          positive regulation of cell division
          cell chemotaxis
          positive regulation of protein tyrosine kinase activity
          positive regulation of ERK1 and ERK2 cascade
          protein kinase C signaling
          cellular response to growth factor stimulus
          cellular response to mycophenolic acid
          positive regulation of glomerular mesangial cell proliferation
          metanephric glomerular mesangial cell development
          reactive oxygen species metabolic process
          positive regulation of calcium ion import
          positive regulation of hyaluronan biosynthetic process
          negative regulation of pri-miRNA transcription from RNA polymerase II promoter
          positive regulation of pri-miRNA transcription from RNA polymerase II promoter
          positive regulation of vascular smooth muscle cell proliferation
          positive regulation of vascular associated smooth muscle cell migration
          negative regulation of vascular smooth muscle cell differentiation
          positive regulation of vascular smooth muscle cell dedifferentiation
          positive regulation of reactive oxygen species metabolic process
          positive regulation of DNA biosynthetic process
          positive regulation of metanephric mesenchymal cell migration
          Ras guanyl-nucleotide exchange factor activity
          platelet-derived growth factor receptor binding
          protein binding
          collagen binding
          growth factor activity
          superoxide-generating NADPH oxidase activator activity
          chemoattractant activity
          identical protein binding
          protein homodimerization activity
          phosphatidylinositol-4,5-bisphosphate 3-kinase activity
          protein heterodimerization activity
          platelet-derived growth factor binding

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