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          System Message

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          LOADING ...
          See other SMAD7 SIRNA Assays ›
          Gene Symbol:
          Smad7
          Gene Name:
          SMAD family member 7
          Gene Aliases:
          Madh7
          Chromosome Location:
          Chr.18: 75367365 - 75395935 on Build GRCm38
          UniGene ID:
          Mm.34407
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID MSS206446
          Size 20 nmol
          Availability Made To Order
          Catalog # 1320001
          Price Contact Us
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Smad7
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001042660.1 NP_001036125.1 4 2494
          GenBank mRNA AB221688.1 - 4 903
          AF015260.1 - 4 903
          AJ000550.1 - 4 2339
          AJ000551.1 - 4 900
          BC137638.1 - 4 976 8860657

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Human: NM_001190821, NM_005904, NM_001190822, NM_001190823, BC074819, and others.
          This siRNA also targets the following transcripts in Rat: NM_030858, XM_006254959, AF159626, AF042499.

          Panther Classification:

          Molecular Function -

          DNA-binding transcription factor gene-specific transcriptional regulator

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          transforming growth factor beta receptor signaling pathway
          negative regulation of peptidyl-threonine phosphorylation
          negative regulation of transcription by competitive promoter binding
          regulation of transforming growth factor beta receptor signaling pathway
          positive regulation of cell-cell adhesion
          negative regulation of transforming growth factor beta receptor signaling pathway
          negative regulation of BMP signaling pathway
          negative regulation of protein ubiquitination
          positive regulation of protein ubiquitination
          positive regulation of proteasomal ubiquitin-dependent protein catabolic process
          regulation of activin receptor signaling pathway
          negative regulation of peptidyl-serine phosphorylation
          adherens junction assembly
          cellular protein complex localization
          intracellular signal transduction
          negative regulation of sequence-specific DNA binding transcription factor activity
          artery morphogenesis
          protein stabilization
          negative regulation of ubiquitin-protein transferase activity
          ventricular cardiac muscle tissue morphogenesis
          regulation of cardiac muscle contraction
          regulation of ventricular cardiac muscle cell membrane depolarization
          pathway-restricted SMAD protein phosphorylation
          negative regulation of pathway-restricted SMAD protein phosphorylation
          ventricular septum morphogenesis
          cellular response to transforming growth factor beta stimulus
          DNA binding
          transcription factor activity, sequence-specific DNA binding
          protein binding
          collagen binding
          beta-catenin binding
          transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
          ubiquitin protein ligase binding
          type I transforming growth factor beta receptor binding
          transcription regulatory region DNA binding
          metal ion binding
          activin binding
          I-SMAD binding

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