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          System Message

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          LOADING ...
          See other TIRAP SIRNA Assays ›
          Gene Symbol:
          Tirap
          Gene Name:
          toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
          Gene Aliases:
          AA407980, C130027E04Rik, Mal, Tlr4ap, Wyatt
          Chromosome Location:
          Chr.9: 35184391 - 35200291 on Build GRCm38
          UniGene ID:
          Mm.23987
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID MSS235918
          Size 20 nmol
          Availability Made To Order
          Catalog # 1320001
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Tirap
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001177845.1 NP_001171316.1 6 595
          NM_001177846.1 NP_001171317.1 6 577
          NM_001177847.1 NP_001171318.1 6 523
          NM_054096.2 NP_473437.2 6 587
          GenBank mRNA AF378130.1 - 6 496
          AF410784.1 - 5 419
          AK036431.1 - 6 516
          AK080135.1 - 6 596
          AK151117.1 - 6 525
          AK168494.1 - 6 515
          BC005584.1 - 3 253 3157913
          BY743490.1 - 6 523

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: XM_001055833, XM_006242794.

          Gene Ontology Categories:

          Function(s) Process(es)

          immune system process
          inflammatory response
          signal transduction
          cell surface receptor signaling pathway
          I-kappaB kinase/NF-kappaB signaling
          activation of JUN kinase activity
          response to bacterium
          myeloid cell differentiation
          positive regulation of B cell proliferation
          response to lipopolysaccharide
          regulation of interferon-beta production
          regulation of interleukin-15 production
          positive regulation of interleukin-12 production
          positive regulation of interleukin-15 production
          positive regulation of interleukin-8 production
          positive regulation of tumor necrosis factor production
          positive regulation of toll-like receptor 2 signaling pathway
          positive regulation of toll-like receptor 3 signaling pathway
          positive regulation of toll-like receptor 4 signaling pathway
          toll-like receptor 5 signaling pathway
          TIRAP-dependent toll-like receptor 4 signaling pathway
          positive regulation of I-kappaB kinase/NF-kappaB signaling
          negative regulation of growth of symbiont in host
          innate immune response
          regulation of innate immune response
          positive regulation of innate immune response
          positive regulation of interleukin-6 biosynthetic process
          positive regulation of JNK cascade
          defense response to Gram-positive bacterium
          positive regulation of NF-kappaB transcription factor activity
          positive regulation of ERK1 and ERK2 cascade
          interleukin-1-mediated signaling pathway
          3'-UTR-mediated mRNA stabilization
          cellular response to bacterial lipopeptide
          cellular response to lipoteichoic acid
          positive regulation of neutrophil chemotaxis
          positive regulation of protein homodimerization activity
          positive regulation of chemokine (C-X-C motif) ligand 1 production
          positive regulation of chemokine (C-X-C motif) ligand 2 production
          protein kinase C binding
          protein binding
          phosphatidylinositol-4,5-bisphosphate binding
          Toll-like receptor 4 binding
          Toll-like receptor 2 binding
          protein homodimerization activity
          protein heterodimerization activity

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