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          System Message

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          LOADING ...
          See other TLR4 SIRNA Assays ›
          Gene Symbol:
          Tlr4
          Gene Name:
          toll-like receptor 4
          Gene Aliases:
          -
          Chromosome Location:
          Chr.5: 82587424 - 82601056 on Build Rnor_6.0
          UniGene ID:
          Rn.14534
          Species:
          Rat
          Species Specific ID (Flybase ID):
          -
          siRNA ID s131042

          Purification
          Size
          Availability Made To Order
          Catalog # 4390771
          Price
          Your Price
          Online offer:
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          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Tlr4
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_019178.1 NP_062051.1 3 2468
          GenBank mRNA AF057025.1 - 3 2490
          FQ233814.1 - 1 522
          GQ175880.1 - 3 2468

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Mouse: NM_021297, JX878358, AF110133, JX878359, AF185285, and others.

          Gene Ontology Categories:

          Function(s) Process(es)

          activation of MAPK activity
          response to hypoxia
          microglial cell activation
          activation of innate immune response
          toll-like receptor signaling pathway
          B cell proliferation involved in immune response
          nitric oxide production involved in inflammatory response
          MyD88-dependent toll-like receptor signaling pathway
          innate immune response-activating signal transduction
          skeletal muscle contraction
          leukotriene metabolic process
          inflammatory response
          response to oxidative stress
          I-kappaB phosphorylation
          response to bacterium
          response to toxic substance
          positive regulation of platelet activation
          response to activity
          immunoglobulin mediated immune response
          positive regulation of B cell proliferation
          lipopolysaccharide-mediated signaling pathway
          response to lipopolysaccharide
          detection of lipopolysaccharide
          response to retinoic acid
          response to progesterone
          interferon-gamma production
          negative regulation of interferon-gamma production
          negative regulation of interleukin-17 production
          negative regulation of interleukin-23 production
          negative regulation of interleukin-6 production
          negative regulation of tumor necrosis factor production
          positive regulation of chemokine production
          positive regulation of interferon-alpha production
          positive regulation of interferon-beta production
          positive regulation of interferon-gamma production
          positive regulation of interleukin-1 production
          positive regulation of interleukin-10 production
          positive regulation of interleukin-12 production
          positive regulation of interleukin-6 production
          positive regulation of interleukin-8 production
          positive regulation of tumor necrosis factor production
          response to insulin
          positive regulation of stress-activated MAPK cascade
          toll-like receptor 4 signaling pathway
          macrophage activation
          positive regulation of NF-kappaB import into nucleus
          positive regulation of tumor necrosis factor biosynthetic process
          positive regulation of apoptotic process
          positive regulation of I-kappaB kinase/NF-kappaB signaling
          response to morphine
          positive regulation of DNA binding
          positive regulation of interleukin-12 biosynthetic process
          innate immune response
          positive regulation of MHC class II biosynthetic process
          positive regulation of interferon-beta biosynthetic process
          positive regulation of interleukin-8 biosynthetic process
          positive regulation of nitric oxide biosynthetic process
          response to ethanol
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of JNK cascade
          positive regulation of lymphocyte proliferation
          regulation of cytokine secretion
          regulation of inflammatory response
          positive regulation of inflammatory response
          positive regulation of peptidyl-tyrosine phosphorylation
          defense response to Gram-negative bacterium
          positive regulation of sequence-specific DNA binding transcription factor activity
          positive regulation of NF-kappaB transcription factor activity
          response to glucocorticoid
          positive regulation of nitric-oxide synthase biosynthetic process
          regulation of sensory perception of pain
          intestinal epithelial structure maintenance
          positive regulation of macrophage cytokine production
          negative regulation of ERK1 and ERK2 cascade
          positive regulation of ERK1 and ERK2 cascade
          positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
          positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
          response to fatty acid
          cellular response to lipopolysaccharide
          cellular response to lipoteichoic acid
          cellular response to mechanical stimulus
          cellular response to retinoic acid
          response to gold nanoparticle
          lipopolysaccharide binding
          lipopolysaccharide receptor activity
          receptor activity
          transmembrane signaling receptor activity
          protein binding
          phosphatidylinositol 3-kinase binding

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