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          System Message

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          LOADING ...
          See other CASP8 SIRNA Assays ›
          Gene Symbol:
          CASP8
          Gene Name:
          caspase 8
          Gene Aliases:
          ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5
          Chromosome Location:
          Chr.2: 201233443 - 201287711 on Build GRCh38
          UniGene ID:
          Hs.599762
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s2426

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price 5,366.00
          Your Price
          Online offer:
          5366.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: CASP8
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001080124.1 NP_001073593.1 4 584
          NM_001080125.1 NP_001073594.1 3 727
          NM_001228.4 NP_001219.2 5 748
          NM_033355.3 NP_203519.1 4 558
          NM_033356.3 NP_203520.1 3 489
          NM_033358.3 NP_203522.1 4 652
          NR_111983.1 3 727
          XM_005246885.1 XP_005246942.1 3 547
          XM_005246886.1 XP_005246943.1 3 473
          XM_005246887.1 XP_005246944.1 4 625
          XM_005246888.1 XP_005246945.1 4 567
          XM_005246889.1 XP_005246946.1 3 444
          XM_005246890.3 XP_005246947.1 3 451
          XM_005246891.4 XP_005246948.1 3 691
          XM_005246892.1 XP_005246949.1 3 444
          XM_005246893.2 XP_005246950.1 3 547
          XM_005246894.3 XP_005246951.1 4 622
          XM_005246895.2 XP_005246952.1 3 547
          XM_006712789.1 XP_006712852.1 4 584
          XM_006712790.3 XP_006712853.1 3 463
          XM_006712793.2 XP_006712856.1 4 625
          GenBank mRNA AB451282.1 - 2 349
          AB451414.1 - 2 349
          AF009620.1 - 2 349
          AF380342.1 - 3 434
          AF422927.1 - 4 572
          AF422928.1 - 4 546
          AF422929.1 - 3 614
          AK310630.1 - 4 625
          AY429525.1 - 2 80
          BC028223.2 - 2 376
          BC068050.1 - 3 439 6421760
          BX395849.2 - 3 438
          CB990598.1 - 4 569
          EU168332.1 - 2 349
          JN657192.1 - 2 311
          U58143.1 - 2 349
          U60520.1 - 5 701
          X98172.1 - 3 640
          X98173.1 - 3 421
          X98176.1 - 4 538
          X98177.1 - 2 349
          X98178.1 - 2 349

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          More Information


          Panther Classification:

          Molecular Function -

          protease

          Gene Ontology Categories:

          Function(s) Process(es)

          proteolysis
          apoptotic process
          activation of cysteine-type endopeptidase activity involved in apoptotic process
          cellular component disassembly involved in execution phase of apoptosis
          cell surface receptor signaling pathway
          response to cold
          regulation of tumor necrosis factor-mediated signaling pathway
          regulation of necrotic cell death
          natural killer cell activation
          macrophage differentiation
          response to cobalt ion
          response to estradiol
          response to lipopolysaccharide
          response to tumor necrosis factor
          TRIF-dependent toll-like receptor signaling pathway
          TRAIL-activated apoptotic signaling pathway
          suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process
          T cell activation
          B cell activation
          positive regulation of I-kappaB kinase/NF-kappaB signaling
          negative regulation of I-kappaB kinase/NF-kappaB signaling
          response to ethanol
          positive regulation of macrophage differentiation
          positive regulation of proteolysis
          response to antibiotic
          protein heterooligomerization
          proteolysis involved in cellular protein catabolic process
          syncytiotrophoblast cell differentiation involved in labyrinthine layer development
          nucleotide-binding oligomerization domain containing signaling pathway
          cellular response to mechanical stimulus
          cellular response to organic cyclic compound
          death-inducing signaling complex assembly
          apoptotic signaling pathway
          extrinsic apoptotic signaling pathway
          execution phase of apoptosis
          activation of cysteine-type endopeptidase activity
          activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
          positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
          regulation of extrinsic apoptotic signaling pathway via death domain receptors
          negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
          cysteine-type endopeptidase activity
          death receptor binding
          tumor necrosis factor receptor binding
          protein binding
          peptidase activity
          cysteine-type peptidase activity
          ubiquitin protein ligase binding
          protein complex binding
          death effector domain binding
          identical protein binding
          scaffold protein binding
          cysteine-type endopeptidase activity involved in apoptotic process
          cysteine-type endopeptidase activity involved in apoptotic signaling pathway

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