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          System Message

          OKCancel
          LOADING ...
          See other CASP8 SIRNA Assays ›
          Gene Symbol:
          CASP8
          Gene Name:
          caspase 8
          Gene Aliases:
          ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5
          Chromosome Location:
          Chr.2: 201233443 - 201287711 on Build GRCh38
          UniGene ID:
          Hs.599762
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s2427
          Validated

          Purification
          Size
          Availability Inventoried
          Catalog # 4390824
          Price 7,898.00
          Your Price
          Online offer:
          7898.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: CASP8
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001080124.1 NP_001073593.1 7 899
          NM_001080125.1 NP_001073594.1 7 1087
          NM_001228.4 NP_001219.2 8 1063
          NM_033355.3 NP_203519.1 8 918
          NM_033356.3 NP_203520.1 6 804
          NM_033358.3 NP_203522.1 7 947
          NR_111983.1 7 1087
          XM_005246885.1 XP_005246942.1 6 862
          XM_005246886.1 XP_005246943.1 7 833
          XM_005246887.1 XP_005246944.1 8 985
          XM_005246888.1 XP_005246945.1 8 927
          XM_005246889.1 XP_005246946.1 7 804
          XM_005246890.3 XP_005246947.1 7 811
          XM_005246891.4 XP_005246948.1 7 1051
          XM_005246892.1 XP_005246949.1 6 759
          XM_005246893.2 XP_005246950.1 6 842
          XM_005246894.3 XP_005246951.1 7 917
          XM_005246895.2 XP_005246952.1 5 797
          XM_006712789.1 XP_006712852.1 8 944
          XM_006712790.3 XP_006712853.1 7 823
          XM_006712793.2 XP_006712856.1 7 920
          XM_011511969.1 XP_011510271.1 5 388
          GenBank mRNA AB451282.1 - 5 664
          AB451414.1 - 5 664
          AF009620.1 - 5 664
          AF380342.1 - 7 794
          AF422927.1 - 7 887
          AF422928.1 - 8 906
          BC028223.2 - 6 736
          BC068050.1 - 6 754 6421760
          BX395849.2 - 6 753
          JN657192.1 - 4 560
          U58143.1 - 6 709
          U60520.1 - 8 1016
          X98172.1 - 7 1000
          X98173.1 - 6 736
          X98175.1 - 3 214
          X98176.1 - 7 833
          X98177.1 - 6 709
          X98178.1 - 5 664

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Mouse: NM_009812, NM_001080126, NM_001277926, AK146758, AK168812, and others.

          Matching Taqman Gene Expression Assay:


          Hs00236278_m1

          Panther Classification:

          Molecular Function -

          protease

          Gene Ontology Categories:

          Function(s) Process(es)

          proteolysis
          apoptotic process
          activation of cysteine-type endopeptidase activity involved in apoptotic process
          cellular component disassembly involved in execution phase of apoptosis
          cell surface receptor signaling pathway
          response to cold
          regulation of tumor necrosis factor-mediated signaling pathway
          regulation of necrotic cell death
          natural killer cell activation
          macrophage differentiation
          response to cobalt ion
          response to estradiol
          response to lipopolysaccharide
          response to tumor necrosis factor
          TRIF-dependent toll-like receptor signaling pathway
          TRAIL-activated apoptotic signaling pathway
          suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process
          T cell activation
          B cell activation
          positive regulation of I-kappaB kinase/NF-kappaB signaling
          negative regulation of I-kappaB kinase/NF-kappaB signaling
          response to ethanol
          positive regulation of macrophage differentiation
          positive regulation of proteolysis
          response to antibiotic
          protein heterooligomerization
          proteolysis involved in cellular protein catabolic process
          syncytiotrophoblast cell differentiation involved in labyrinthine layer development
          nucleotide-binding oligomerization domain containing signaling pathway
          cellular response to mechanical stimulus
          cellular response to organic cyclic compound
          death-inducing signaling complex assembly
          apoptotic signaling pathway
          extrinsic apoptotic signaling pathway
          execution phase of apoptosis
          activation of cysteine-type endopeptidase activity
          activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
          positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
          regulation of extrinsic apoptotic signaling pathway via death domain receptors
          negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
          cysteine-type endopeptidase activity
          death receptor binding
          tumor necrosis factor receptor binding
          protein binding
          peptidase activity
          cysteine-type peptidase activity
          ubiquitin protein ligase binding
          protein complex binding
          death effector domain binding
          identical protein binding
          scaffold protein binding
          cysteine-type endopeptidase activity involved in apoptotic process
          cysteine-type endopeptidase activity involved in apoptotic signaling pathway

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          Host server : magellan-search-blue-55ff9ddd88-ctdjb:80/100.66.76.55:80.
          git-commit: d366ff9721d93504b2ac26a183b2b3e3d0e7d9ec
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.42.0-2026.01.03-1.0