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          System Message

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          LOADING ...
          See other NOD2 SIRNA Assays ›
          Gene Symbol:
          NOD2
          Gene Name:
          nucleotide binding oligomerization domain containing 2
          Gene Aliases:
          ACUG, BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, NOD2B, PSORAS1
          Chromosome Location:
          Chr.16: 50693581 - 50733077 on Build GRCh38
          UniGene ID:
          Hs.592072
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s34484

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price 5,366.00
          Your Price
          Online offer:
          5366.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: NOD2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001293557.1 NP_001280486.1 4 2565
          NM_022162.2 NP_071445.1 5 2605
          XM_005256084.3 XP_005256141.1 5 2509
          XM_006721242.3 XP_006721305.1 5 2509
          XM_011523259.2 XP_011521561.1 3 2321
          XM_017023535.1 XP_016879024.1 3 3879
          XM_017023536.1 XP_016879025.1 4 2036
          XM_017023537.1 XP_016879026.1 3 1930
          XM_017023538.1 XP_016879027.1 4 2031
          GenBank mRNA AF178930.1 - 5 2605
          AY187233.1 - 2 218
          AY187234.1 - 2 246
          AY187239.1 - 2 218
          AY187241.1 - 2 218

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          More Information


          Panther Classification:

          Molecular Function -

          non-motor microtubule binding protein

          Gene Ontology Categories:

          Function(s) Process(es)

          activation of MAPK activity
          cytokine production involved in immune response
          cytokine secretion involved in immune response
          positive regulation of dendritic cell antigen processing and presentation
          positive regulation of type 2 immune response
          defense response
          JNK cascade
          detection of biotic stimulus
          detection of bacterium
          maintenance of gastrointestinal epithelium
          response to muramyl dipeptide
          detection of muramyl dipeptide
          positive regulation of interleukin-1 beta production
          positive regulation of interleukin-10 production
          positive regulation of interleukin-17 production
          positive regulation of interleukin-6 production
          positive regulation of interleukin-8 production
          positive regulation of tumor necrosis factor production
          positive regulation of stress-activated MAPK cascade
          activation of MAPK activity involved in innate immune response
          intracellular signal transduction
          defense response to bacterium
          positive regulation of I-kappaB kinase/NF-kappaB signaling
          positive regulation of phosphatidylinositol 3-kinase activity
          innate immune response
          positive regulation of Notch signaling pathway
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of JNK cascade
          positive regulation of gamma-delta T cell activation
          positive regulation of epithelial cell proliferation
          positive regulation of interleukin-1 beta secretion
          regulation of inflammatory response
          positive regulation of B cell activation
          positive regulation of NF-kappaB transcription factor activity
          protein oligomerization
          positive regulation of oxidoreductase activity
          positive regulation of nitric-oxide synthase biosynthetic process
          positive regulation of prostaglandin-endoperoxide synthase activity
          positive regulation of ERK1 and ERK2 cascade
          nucleotide-binding oligomerization domain containing signaling pathway
          nucleotide-binding oligomerization domain containing 2 signaling pathway
          cellular response to muramyl dipeptide
          positive regulation of cytokine production involved in inflammatory response
          positive regulation of NIK/NF-kappaB signaling
          negative regulation of macrophage apoptotic process
          positive regulation of prostaglandin-E synthase activity
          actin binding
          protein binding
          ATP binding
          enzyme binding
          protein kinase binding
          Hsp70 protein binding
          muramyl dipeptide binding
          peptidoglycan binding
          CARD domain binding
          Hsp90 protein binding

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