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          System Message

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          LOADING ...
          See other PTPN11 SIRNA Assays ›
          Gene Symbol:
          PTPN11
          Gene Name:
          protein tyrosine phosphatase, non-receptor type 11
          Gene Aliases:
          BPTP3, CFC, JMML, METCDS, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2
          Chromosome Location:
          Chr.12: 112418732 - 112509913 on Build GRCh38
          UniGene ID:
          Hs.506852
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s531838

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price 5,366.00
          Your Price
          Online offer:
          5366.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: PTPN11
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_002834.3 NP_002825.3 8, 9 1315
          NM_080601.1 NP_542168.1 8, 9 1315
          XM_006719526.2 XP_006719589.1 8, 9 1093
          XM_011538613.2 XP_011536915.1 8, 9 1129
          XM_017019722.1 XP_016875211.1 8, 9 1132
          GenBank mRNA AK289854.1 - 8, 9 1093
          BC008692.1 - 8, 9 1138 3872007
          BT007106.1 - 7, 8 935
          D13540.1 - 8, 9 1091
          L03535.1 - 8, 9 1048
          L07527.1 - 8, 9 1088
          L08807.1 - 8, 9 1133
          X70766.1 - 8, 9 1064

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: D83016, U05963, U57499, U09307.

          Panther Classification:

          Molecular Function -

          protein phosphatase

          Gene Ontology Categories:

          Function(s) Process(es)

          DNA damage checkpoint
          activation of MAPK activity
          triglyceride metabolic process
          epidermal growth factor receptor signaling pathway
          integrin-mediated signaling pathway
          axonogenesis
          brain development
          heart development
          fibroblast growth factor receptor signaling pathway
          hormone-mediated signaling pathway
          regulation of phosphatidylinositol 3-kinase signaling
          cerebellar cortex formation
          platelet activation
          platelet formation
          T cell costimulation
          microvillus organization
          abortive mitotic cell cycle
          regulation of cell adhesion mediated by integrin
          negative regulation of cell adhesion mediated by integrin
          multicellular organism growth
          organ growth
          peptidyl-tyrosine dephosphorylation
          megakaryocyte development
          phosphatidylinositol-3-phosphate biosynthetic process
          atrioventricular canal development
          ERBB signaling pathway
          regulation of multicellular organism growth
          hormone metabolic process
          glucose homeostasis
          regulation of protein complex assembly
          positive regulation of mitotic cell cycle
          negative regulation of insulin secretion
          regulation of protein export from nucleus
          phosphatidylinositol phosphorylation
          positive regulation of hormone secretion
          platelet-derived growth factor receptor signaling pathway
          neurotrophin TRK receptor signaling pathway
          ephrin receptor signaling pathway
          phosphatidylinositol-mediated signaling
          multicellular organismal reproductive process
          genitalia development
          inner ear development
          homeostasis of number of cells within a tissue
          leukocyte migration
          negative regulation of cortisol secretion
          Bergmann glial cell differentiation
          negative regulation of growth hormone secretion
          face morphogenesis
          regulation of type I interferon-mediated signaling pathway
          intestinal epithelial cell migration
          positive regulation of ERK1 and ERK2 cascade
          positive regulation of glucose import in response to insulin stimulus
          phosphoprotein phosphatase activity
          protein tyrosine phosphatase activity
          non-membrane spanning protein tyrosine phosphatase activity
          SH3/SH2 adaptor activity
          insulin receptor binding
          protein binding
          1-phosphatidylinositol-3-kinase activity
          protein domain specific binding
          receptor tyrosine kinase binding
          D1 dopamine receptor binding
          phospholipase binding
          insulin receptor substrate binding
          phosphatidylinositol-4,5-bisphosphate 3-kinase activity
          peptide hormone receptor binding

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          git-commit: d366ff9721d93504b2ac26a183b2b3e3d0e7d9ec
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