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          System Message

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          LOADING ...
          See other SMAD2 SIRNA Assays ›
          Gene Symbol:
          SMAD2
          Gene Name:
          SMAD family member 2
          Gene Aliases:
          JV18, JV18-1, MADH2, MADR2, hMAD-2, hSMAD2
          Chromosome Location:
          Chr.18: 47833095 - 47931193 on Build GRCh38
          UniGene ID:
          Hs.12253
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s8399

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price 5,366.00
          Your Price
          Online offer:
          5366.0
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: SMAD2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001003652.3 NP_001003652.1 10 1621
          NM_001135937.2 NP_001129409.1 9 1531
          NM_005901.5 NP_005892.1 10 1513
          XM_005258259.3 XP_005258316.1 11 1754
          XM_006722451.3 XP_006722514.1 11 1766
          XM_011525984.2 XP_011524286.1 10 1110
          XM_011525985.2 XP_011524287.1 12 1813
          XM_017025745.1 XP_016881234.1 12 1852
          XM_017025746.1 XP_016881235.1 10 1664
          XM_017025747.1 XP_016881236.1 11 1739
          XM_017025748.1 XP_016881237.1 12 1825
          XM_017025750.1 XP_016881239.1 11 1714
          GenBank mRNA AF027964.1 - 10 1327
          AK299218.1 - 9 1227
          AK312963.1 - 9 1350
          BC014840.1 - 10 1469 4449540
          BC025699.1 - 10 1327 5221801
          BT007422.1 - 9 1221
          U59911.1 - 10 1320
          U65019.1 - 9 1257
          U68018.1 - 9 1276

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          More Information


          Panther Classification:

          Molecular Function -

          DNA-binding transcription factor gene-specific transcriptional regulator

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          ureteric bud development
          in utero embryonic development
          endoderm formation
          mesoderm formation
          transcription from RNA polymerase II promoter
          transforming growth factor beta receptor signaling pathway
          common-partner SMAD protein phosphorylation
          SMAD protein complex assembly
          zygotic specification of dorsal/ventral axis
          gastrulation
          negative regulation of cell proliferation
          response to glucose
          post-embryonic development
          anterior/posterior pattern specification
          positive regulation of epithelial to mesenchymal transition
          regulation of transforming growth factor beta receptor signaling pathway
          signal transduction involved in regulation of gene expression
          insulin secretion
          lung development
          negative regulation of transforming growth factor beta receptor signaling pathway
          positive regulation of BMP signaling pathway
          pancreas development
          primary miRNA processing
          activin receptor signaling pathway
          somatic stem cell population maintenance
          organ growth
          intracellular signal transduction
          nodal signaling pathway
          cell fate commitment
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          paraxial mesoderm morphogenesis
          embryonic foregut morphogenesis
          embryonic cranial skeleton morphogenesis
          regulation of binding
          palate development
          pericardium development
          SMAD protein signal transduction
          response to cholesterol
          positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry
          RNA polymerase II core promoter proximal region sequence-specific DNA binding
          transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
          DNA binding
          chromatin binding
          double-stranded DNA binding
          transcription factor activity, sequence-specific DNA binding
          transforming growth factor beta receptor binding
          protein binding
          transcription factor binding
          phosphatase binding
          transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
          ubiquitin protein ligase binding
          activating transcription factor binding
          type I transforming growth factor beta receptor binding
          enhancer binding
          protein homodimerization activity
          SMAD binding
          metal ion binding
          protein heterodimerization activity
          co-SMAD binding
          I-SMAD binding
          R-SMAD binding

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          Host server : magellan-search-green-55658555d6-trpdr:80/100.66.79.83:80.
          git-commit: ec8e7df5f8fec8d765bd419205f1b5046a016d37
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.41.0-Offline