f254 Plaice

f254 Plaice Scientific Information

Type:

Whole Allergen

Display Name:

Plaice

Allergen code:

f254

Family:

Pleuronectidae

Latin Name:

Pleuronectes platessa

Other Names:

Plaice

WHO/ICD-11 code:

XM95M8

(ICD-11 is currently under implementation by WHO and the ICD-11 codes displayed in the encyclopedia may not yet be available in all countries)

Route of Exposure

Cooked, fried or otherwise prepared in various fish dishes

Clinical Relevance

Specific IgE antibodies have been measured in atopic dermatitis patients (1, 2), and in food-allergic children (3) using Pharmacia CAP System. The clinical sensitivity and specificity of f254 Plaice was reported to be 86% and 94% respectively (4).

Other Topics

A salt water flat fish with white flesh, Plaice is commercially fished on both sides of the Atlantic. Its length is rarely over 60 cm, although before it was heavily fished, it could be over one meter. Species within groups of fish, like Gadiformes (examples: codfish and hake) and Scombroid fishes (examples: mackerel and tuna) seem to share allergenic components. The overlap of allergen specificity between the groups seems to be moderate or even small. Specific IgE antibodies have been measured in atopic dermatitis patients (1, 2), and in food-allergic children (3) using Pharmacia CAP System. The clinical sensitivity and specificity of f254 Plaice was reported to be 86% and 94% respectively (4).

Molecular Aspects

Cross Reactivity

Species within groups of fish, like Gadiformes (examples: codfish and hake) and Scombroid fish (examples: mackerel and tuna) seem to share allergenic components. The overlap of allergen specificity between the groups seems to be moderate or even small.

Compiled By

Last reviewed : June 2022

References

Konatsu H, Miyagawa K, Ikezawa Z. Study of clinical efficacy of Pharmacia CAP System new allergens in patients with atopic dermatitis. Japanese Soc Allergol 1992.
Lindqvist A, Ikezawa Z, Tanaka A, Yman L. Seafood specific IgE in atopic dermatitis. Ann Allergy1993;70:58.
Matsumaru S, Artia M et al. Clinical evaluation of Pharmacia CAP System new allergens for fish, vegetables, fruits and grains. Jap Soc Ped Allergol 1992.
Hansen TK, Abrahamsen L, Bindslev-Jensen C, Poulsen LK. Results of the CAP System and Immunoblotting in clinically fish allergic adults. Allergologie 1995;18:407.