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Bacterial co-infection may occur in approximately one-fourth of hospitalized patients with influenza.1
PCT has a high negative predictive value (NPV) at ≤ 0.25 μg/L, which aids in determining the need for antibiotics in LRTI. When uncertainty exists with an initial negative PCT result, repeating the test within 6 to 24 hours can assist with confirming the initial result, and indicate that antibiotics may no longer be necessary.
In this case, PCT aided in ruling out bacterial infection, allowing the clinicians to avoid giving unnecessary antibiotics and to continue with the appropriate anti-viral therapy.