Michael R. Broyles
PharmD – Director of Medical Affairs, Thermo Fisher Scientific
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Lactate is a marker of anaerobic metabolism and has a low sensitivity and specificity for bacterial infection. It should not guide antibiotictherapy.
If lactate is elevated with a bacterial infection, the patient is likely septic or in septic shock.
Lactate provides information about perfusion not bacterial infection. PCT provides information about bacterial infection, not perfusion.