Product References
Regulation of CTCF loop formation during pancreatic cell differentiation.
Nature communications
Lyu X,Rowley MJ,Kulik MJ,Dalton S,Corces VG
100-50 was used in In vitro experiments to suggest an important role for CTCF and cohesin in controlling gene expression during cell differentiation.
Mon Oct 09 00:00:00 EDT 2023
Protocol to generate human pluripotent stem cell-derived pancreatic β cells through methionine and zinc deprivation.
STAR protocols
Sim EZ,Enomoto T,Shiraki N,Kume S
100-50 was used in In vitro experiments to describe steps for a short 5-h methionine deprivation pretreatment followed by the application of zinc-deprived media at definitive endoderm differentiation stages to improve differentiation efficiency.
Wed Mar 22 00:00:00 EDT 2023
FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity.
Cell metabolism
Wieder N,Fried JC,Kim C,Sidhom EH,Brown MR,Marshall JL,Arevalo C,Dvela-Levitt M,Kost-Alimova M,Sieber J,Gabriel KR,Pacheco J,Clish C,Abbasi HS,Singh S,Rutter JC,Therrien M,Yoon H,Lai ZW,Baublis A,Subramanian R,Devkota R,Small J,Sreekanth V,Han M,Lim D,Carpenter AE,Flannick J,Finucane H,Haigis MC,Claussnitzer M,Sheu E,Stevens B,Wagner BK,Choudhary A,Shaw JL,Pablo JL,Greka A
100-50 was used in In vitro experiments to find that c-MAF-inducing protein (CMIP) protects cells from FFA exposure by modulating Akt signaling.
Tue May 02 00:00:00 EDT 2023
Generation of induced pluripotent stem cell-derived beta-cells in blood amino acids-like medium.
Biology open
Ali M,Kato Y,Shiraki N,Kume S
100-50 was used in In vitro experiments to establish a defined culture system to derive SC-β-cells using a blood amino acids-like medium (BALM).
Wed Mar 15 00:00:00 EDT 2023
Differentiating functional human islet-like aggregates from pluripotent stem cells.
STAR protocols
Barsby T,Ibrahim H,Lithovius V,Montaser H,Balboa D,Vähäkangas E,Chandra V,Saarimäki-Vire J,Otonkoski T
100-50 was used in In vitro experiments to present here a robust and reliable protocol by which to differentiate pancreatic islet-like aggregates (SC-islets) from human pluripotent stem cells.
Fri Dec 16 00:00:00 EST 2022
CODEX, a neural network approach to explore signaling dynamics landscapes.
Molecular systems biology
Jacques MA,Dobrzyński M,Gagliardi PA,Sznitman R,Pertz O
Thu Apr 01 00:00:00 EDT 2021
Therapeutically targeting tumor microenvironment-mediated drug resistance in estrogen receptor-positive breast cancer.
The Journal of experimental medicine
Shee K,Yang W,Hinds JW,Hampsch RA,Varn FS,Traphagen NA,Patel K,Cheng C,Jenkins NP,Kettenbach AN,Demidenko E,Owens P,Faber AC,Golub TR,Straussman R,Miller TW
Mon Mar 05 00:00:00 EST 2018
Betacellulin regulates the proliferation and differentiation of retinal progenitor cells in vitro.
Journal of cellular and molecular medicine
Zhang D,Shen B,Zhang Y,Ni N,Wang Y,Fan X,Sun H,Gu P
Mon Jan 01 00:00:00 EST 2018
Image-Based Profiling Can Discriminate the Effects of Inhibitors on Signaling Pathways under Differential Ligand Stimulation.
SLAS discovery : advancing life sciences R & D
Tanabe K,Inagaki A,Henmi Y,Satake M
100-50 was used in Cell Culture to investigate different cellular stimulation effects on efficacy of image-based compound profiling.
Sun Apr 01 00:00:00 EDT 2018
Insulin mutations impair beta-cell development in a patient-derived iPSC model of neonatal diabetes.
eLife
Balboa D,Saarimäki-Vire J,Borshagovski D,Survila M,Lindholm P,Galli E,Eurola S,Ustinov J,Grym H,Huopio H,Partanen J,Wartiovaara K,Otonkoski T
100-50 was used in In vitro experiments to demonstrate that misfolded proinsulin impairs developing beta-cell proliferation without increasing apoptosis.
Fri Nov 09 00:00:00 EST 2018
EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics.
Cell
Freed DM,Bessman NJ,Kiyatkin A,Salazar-Cavazos E,Byrne PO,Moore JO,Valley CC,Ferguson KM,Leahy DJ,Lidke DS,Lemmon MA
Thu Oct 19 00:00:00 EDT 2017
Inhibition of epidermal growth factor receptor tyrosine kinase ameliorates collagen-induced arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Swanson CD,Akama-Garren EH,Stein EA,Petralia JD,Ruiz PJ,Edalati A,Lindstrom TM,Robinson WH
Sun Apr 01 00:00:00 EDT 2012
Differentiation of mesenchymal stem cells derived from pancreatic islets and bone marrow into islet-like cell phenotype.
PloS one
Zanini C,Bruno S,Mandili G,Baci D,Cerutti F,Cenacchi G,Izzi L,Camussi G,Forni M
Mon Aug 27 00:00:00 EDT 2012