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Invitrogen
Human PI4KB (aa 341-453) Control Fragment Recombinant Protein
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Product Details
RP-89167
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
TLPTKEQKTQRLISELSLLNHKLPARVWLPTAGFDHHVVRVPHTQAVVLNSKDKAPYLIYVEVLECENFDTTSVPARIPENRIRSTRSVENLPECGITHEQRAGSFSTVPNYD
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (100%), Rat (100%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52270. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
PI4KB and PI4KA are the two human type III PI4 kinases, which share sequence similarly with PI3 kinases and phosphorylate the 4 position of phosphotidyl inositol. Transporter for alanine, serine, cysteine, and threonine. Exhibits sodium dependence. Target protein phosphorylates phosphatidylinositol (PtdIns) at the D4 position of the inositol ring; may play a role in neuronal differentiation and maturation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: NPIK; phosphatidylinositol 4-kinase; Phosphatidylinositol 4-kinase beta; phosphatidylinositol 4-kinase, catalytic, beta; phosphatidylinositol 4-kinase, wortmannin-sensitive; PI4K-beta; PI4K92; PI4KIII; PtdIns 4-kinase beta; type III phosphatidylinositol 4-kinase beta
Gene Aliases: NPIK; PI4K-BETA; PI4K92; PI4KB; PI4KBETA; PI4KIIIBETA; PIK4CB
UniProt ID: (Human) Q9UBF8
Entrez Gene ID: (Human) 5298
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