Product References
Keratin-mediated hair growth and its underlying biological mechanism.
Communications biology
An SY,Kim HS,Kim SY,Van SY,Kim HJ,Lee JH,Han SW,Kwon IK,Lee CK,Do SH,Hwang YS
100-35B was used in Cell Culture to provide an evidence on initiating hair regeneration and insight into the biological function of keratin exposed from apoptotic epithelial cells in tissue regeneration and development.
Sat Nov 19 00:00:00 EST 2022
A primary rodent triculture model to investigate the role of glia-neuron crosstalk in regulation of neuronal activity.
Frontiers in aging neuroscience
Phadke L,Lau DHW,Aghaizu ND,Ibarra S,Navarron CM,Granat L,Magno L,Whiting P,Jolly S
100-35B was used in Cell Culture to present a functional triculture model, which, due to its more complete cellular composition, is a more relevant model than standard cocultures.
Thu Dec 22 00:00:00 EST 2022
The TSP-1 domain of the matricellular protein CCN5 is essential for its nuclear localization and anti-fibrotic function.
PloS one
Song MH,Jo Y,Kim YK,Kook H,Jeong D,Park WJ
100-35B was used in In vitro experiments to study the roles of the CCN5 structural domains in the context of the reverse trans-differentiation of myofibroblasts (MyoFBs) to fibroblasts (FBs).
Fri Apr 29 00:00:00 EDT 2022
Histone deacetylase 9 promotes endothelial-mesenchymal transition and an unfavorable atherosclerotic plaque phenotype.
The Journal of clinical investigation
Lecce L,Xu Y,V'Gangula B,Chandel N,Pothula V,Caudrillier A,Santini MP,d'Escamard V,Ceholski DK,Gorski PA,Ma L,Koplev S,Bjørklund MM,Björkegren JL,Boehm M,Bentzon JF,Fuster V,Kim HW,Weintraub NL,Baker AH,Bernstein E,Kovacic JC
Mon Aug 02 00:00:00 EDT 2021
White matter aging drives microglial diversity.
Neuron
Safaiyan S,Besson-Girard S,Kaya T,Cantuti-Castelvetri L,Liu L,Ji H,Schifferer M,Gouna G,Usifo F,Kannaiyan N,Fitzner D,Xiang X,Rossner MJ,Brendel M,Gokce O,Simons M
Wed Apr 07 00:00:00 EDT 2021
TGF-β isoforms inhibit hepatitis C virus propagation in transforming growth factor beta/SMAD protein signalling pathway dependent and independent manners.
Journal of cellular and molecular medicine
Zou LL,Li JR,Li H,Tan JL,Wang MX,Liu NN,Gao RM,Yan HY,Wang XK,Dong B,Li YH,Peng ZG
Thu Apr 01 00:00:00 EDT 2021
Human microglia states are conserved across experimental models and regulate neural stem cell responses in chimeric organoids.
Cell stem cell
Popova G,Soliman SS,Kim CN,Keefe MG,Hennick KM,Jain S,Li T,Tejera D,Shin D,Chhun BB,McGinnis CS,Speir M,Gartner ZJ,Mehta SB,Haeussler M,Hengen KB,Ransohoff RR,Piao X,Nowakowski TJ
100-35B was used in Cell Culture to compare human microglia states across culture models, including cultured primary and pluripotent stem cell-derived microglia.
Thu Dec 02 00:00:00 EST 2021
Loss of endothelial glucocorticoid receptor accelerates diabetic nephropathy.
Nature communications
Srivastava SP,Zhou H,Setia O,Liu B,Kanasaki K,Koya D,Dardik A,Fernandez-Hernando C,Goodwin J
Thu Apr 22 00:00:00 EDT 2021
Loss of endothelial glucocorticoid receptor accelerates diabetic nephropathy.
Nature communications
Srivastava SP,Zhou H,Setia O,Liu B,Kanasaki K,Koya D,Dardik A,Fernandez-Hernando C,Goodwin J
Thu Apr 22 00:00:00 EDT 2021
Bioactive decellularized cardiac extracellular matrix-based hydrogel as a sustained-release platform for human adipose tissue-derived stromal cell-secreted factors.
Biomedical materials (Bristol, England)
Liguori TTA,Liguori GR,van Dongen JA,Moreira LFP,Harmsen MC
100-35B was used in Cell Culture to show that the factors secreted by the hydrogel are biologically active as these influence cell behavior.
Wed Feb 24 00:00:00 EST 2021
Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis.
Cell research
Wu J,Song D,Li Z,Guo B,Xiao Y,Liu W,Liang L,Feng C,Gao T,Chen Y,Li Y,Wang Z,Wen J,Yang S,Liu P,Wang L,Wang Y,Peng L,Stacey GN,Hu Z,Feng G,Li W,Huo Y,Jin R,Shyh-Chang N,Zhou Q,Wang L,Hu B,Dai H,Hao J
Tue Sep 01 00:00:00 EDT 2020
Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region.
EMBO molecular medicine
Schlepckow K,Monroe KM,Kleinberger G,Cantuti-Castelvetri L,Parhizkar S,Xia D,Willem M,Werner G,Pettkus N,Brunner B,Sülzen A,Nuscher B,Hampel H,Xiang X,Feederle R,Tahirovic S,Park JI,Prorok R,Mahon C,Liang CC,Shi J,Kim DJ,Sabelström H,Huang F,Di Paolo G,Simons M,Lewcock JW,Haass C
Tue Apr 07 00:00:00 EDT 2020
Knockout of reactive astrocyte activating factors slows disease progression in an ALS mouse model.
Nature communications
Guttenplan KA,Weigel MK,Adler DI,Couthouis J,Liddelow SA,Gitler AD,Barres BA
Mon Jul 27 00:00:00 EDT 2020
Vitamin C supports conversion of human γδ T cells into FOXP3-expressing regulatory cells by epigenetic regulation.
Scientific reports
Kouakanou L,Peters C,Sun Q,Floess S,Bhat J,Huehn J,Kabelitz D
Thu Apr 16 00:00:00 EDT 2020
Targeting all transforming growth factor-β isoforms with an Fc chimeric receptor impairs tumor growth and angiogenesis of oral squamous cell cancer.
The Journal of biological chemistry
Takahashi K,Akatsu Y,Podyma-Inoue KA,Matsumoto T,Takahashi H,Yoshimatsu Y,Koinuma D,Shirouzu M,Miyazono K,Watabe T
Fri Sep 04 00:00:00 EDT 2020
Small molecules targeting RORγt inhibit autoimmune disease by suppressing Th17 cell differentiation.
Cell death & disease
Tan J,Liu H,Huang M,Li N,Tang S,Meng J,Tang S,Zhou H,Kijlstra A,Yang P,Hou S
Sat Aug 22 00:00:00 EDT 2020
Oxidative stress enhanced the transforming growth factor-β2-induced epithelial-mesenchymal transition through chemokine ligand 1 on ARPE-19 cell.
Scientific reports
Yang IH,Lee JJ,Wu PC,Kuo HK,Kuo YH,Huang HM
Wed Mar 04 00:00:00 EST 2020
Methotrexate Chemotherapy Induces Persistent Tri-glial Dysregulation that Underlies Chemotherapy-Related Cognitive Impairment.
Cell
Gibson EM,Nagaraja S,Ocampo A,Tam LT,Wood LS,Pallegar PN,Greene JJ,Geraghty AC,Goldstein AK,Ni L,Woo PJ,Barres BA,Liddelow S,Vogel H,Monje M
Thu Jan 10 00:00:00 EST 2019
Adipose tissue-derived stromal cells' conditioned medium modulates endothelial-mesenchymal transition induced by IL-1β/TGF-β2 but does not restore endothelial function.
Cell proliferation
Liguori TTA,Liguori GR,Moreira LFP,Harmsen MC
100-35B was used in In vitro experiments to demonstrate that ASC-CMed reduces IL-1β/TGF-β2-induced EndMT as observed by the loss of mesenchymal markers.
Fri Nov 01 00:00:00 EDT 2019
Deciphering the complex role of thrombospondin-1 in glioblastoma development.
Nature communications
Daubon T,Léon C,Clarke K,Andrique L,Salabert L,Darbo E,Pineau R,Guérit S,Maitre M,Dedieu S,Jeanne A,Bailly S,Feige JJ,Miletic H,Rossi M,Bello L,Falciani F,Bjerkvig R,Bikfalvi A
Fri Mar 08 00:00:00 EST 2019
A Combination of Ontogeny and CNS Environment Establishes Microglial Identity.
Neuron
Bennett FC,Bennett ML,Yaqoob F,Mulinyawe SB,Grant GA,Hayden Gephart M,Plowey ED,Barres BA
Wed Jun 27 00:00:00 EDT 2018
Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures.
Neuron
Bohlen CJ,Bennett FC,Tucker AF,Collins HY,Mulinyawe SB,Barres BA
Wed May 17 00:00:00 EDT 2017
Proteomic characterization of epicardial-myocardial signaling reveals novel regulatory networks including a role for NF-κB in epicardial EMT.
PloS one
Li Y,Urban A,Midura D,Simon HG,Wang QT
100-35B was used in Cell Culture to characterise the secretome of embryonic chicken EPDC-heart explant co-cultures.
Mon Aug 28 00:00:00 EDT 2017
Dynamic regulation of canonical TGFβ signalling by endothelial transcription factor ERG protects from liver fibrogenesis.
Nature communications
Dufton NP,Peghaire CR,Osuna-Almagro L,Raimondi C,Kalna V,Chauhan A,Webb G,Yang Y,Birdsey GM,Lalor P,Mason JC,Adams DH,Randi AM
Thu Oct 12 00:00:00 EDT 2017
Mitochondrial biogenesis is required for axonal growth.
Development (Cambridge, England)
Vaarmann A,Mandel M,Zeb A,Wareski P,Liiv J,Kuum M,Antsov E,Liiv M,Cagalinec M,Choubey V,Kaasik A
100-35B was used in Sample Preparation (Western Blotting) to determine the role of mitochondrial biogenesis and ATP production in neuronal growth.
Wed Jun 01 00:00:00 EDT 2016
Development and characterization of human monoclonal antibodies that neutralize multiple TGFβ isoforms.
mAbs
Bedinger D,Lao L,Khan S,Lee S,Takeuchi T,Mirza AM
100-35B was used in Surface Plasmon Resonance to study the number of antibodies that bind and neutralize various combinations of TGFβ1, 2 or 3 using fully human antibody phage display libraries.
Tue Dec 13 00:00:00 EST 2016
Effect of Antifibrotic MicroRNAs Crosstalk on the Action of N-acetyl-seryl-aspartyl-lysyl-proline in Diabetes-related Kidney Fibrosis.
Scientific reports
Srivastava SP,Shi S,Kanasaki M,Nagai T,Kitada M,He J,Nakamura Y,Ishigaki Y,Kanasaki K,Koya D
Mon Jul 18 00:00:00 EDT 2016
An Alzheimer Disease-linked Rare Mutation Potentiates Netrin Receptor Uncoordinated-5C-induced Signaling That Merges with Amyloid β Precursor Protein Signaling.
The Journal of biological chemistry
Hashimoto Y,Toyama Y,Kusakari S,Nawa M,Matsuoka M
Fri Jun 03 00:00:00 EDT 2016
An Alzheimer Disease-linked Rare Mutation Potentiates Netrin Receptor Uncoordinated-5C-induced Signaling That Merges with Amyloid β Precursor Protein Signaling.
The Journal of biological chemistry
Hashimoto Y,Toyama Y,Kusakari S,Nawa M,Matsuoka M
Fri Jun 03 00:00:00 EDT 2016
Rescue of neonatal cardiac dysfunction in mice by administration of cardiac progenitor cells in utero.
Nature communications
Liu X,Hall SRR,Wang Z,Huang H,Ghanta S,Di Sante M,Leri A,Anversa P,Perrella MA
Mon Nov 23 00:00:00 EST 2015
Embryonic mechanical and soluble cues regulate tendon progenitor cell gene expression as a function of developmental stage and anatomical origin.
Journal of biomechanics
Brown JP,Finley VG,Kuo CK
Fri Jan 03 00:00:00 EST 2014
Endothelial lineage differentiation from induced pluripotent stem cells is regulated by microRNA-21 and transforming growth factor β2 (TGF-β2) pathways.
The Journal of biological chemistry
Di Bernardini E,Campagnolo P,Margariti A,Zampetaki A,Karamariti E,Hu Y,Xu Q
Fri Feb 07 00:00:00 EST 2014
Neuroblastoma-derived TGF-β1 modulates the chemokine receptor repertoire of human resting NK cells.
Journal of immunology (Baltimore, Md. : 1950)
Castriconi R,Dondero A,Bellora F,Moretta L,Castellano A,Locatelli F,Corrias MV,Moretta A,Bottino C
Wed May 15 00:00:00 EDT 2013
Adenosine A₂A receptor agonist-mediated increase in donor-derived regulatory T cells suppresses development of graft-versus-host disease.
Journal of immunology (Baltimore, Md. : 1950)
Han KL,Thomas SV,Koontz SM,Changpriroa CM,Ha SK,Malech HL,Kang EM
Tue Jan 01 00:00:00 EST 2013
Protocadherins mediate dendritic self-avoidance in the mammalian nervous system.
Nature
Lefebvre JL,Kostadinov D,Chen WV,Maniatis T,Sanes JR
Thu Aug 23 00:00:00 EDT 2012
A soluble bone morphogenetic protein type IA receptor increases bone mass and bone strength.
Proceedings of the National Academy of Sciences of the United States of America
Baud'huin M,Solban N,Cornwall-Brady M,Sako D,Kawamoto Y,Liharska K,Lath D,Bouxsein ML,Underwood KW,Ucran J,Kumar R,Pobre E,Grinberg A,Seehra J,Canalis E,Pearsall RS,Croucher PI
Tue Jul 24 00:00:00 EDT 2012
Transforming growth factor-beta promotes rhinovirus replication in bronchial epithelial cells by suppressing the innate immune response.
PloS one
Bedke N,Sammut D,Green B,Kehagia V,Dennison P,Jenkins G,Tatler A,Howarth PH,Holgate ST,Davies DE
Thu Mar 07 00:00:00 EST 2013
Transforming growth factor-beta promotes rhinovirus replication in bronchial epithelial cells by suppressing the innate immune response.
PloS one
Bedke N,Sammut D,Green B,Kehagia V,Dennison P,Jenkins G,Tatler A,Howarth PH,Holgate ST,Davies DE
Thu Mar 07 00:00:00 EST 2013
Transforming growth factor-beta inhibits the expression of clock genes.
Annals of the New York Academy of Sciences
Gast H,Gordic S,Petrzilka S,Lopez M,Müller A,Gietl A,Hock C,Birchler T,Fontana A
100-35B was used in Cell Culture to show that TGF-β2 did not alter the expression of brain and muscle Arnt-like protein-1 (Bmal1).
Sun Jul 01 00:00:00 EDT 2012
Toxin-induced RhoA activity mediates CCL1-triggered signal transducers and activators of transcription protein signaling.
The Journal of biological chemistry
Reipschläger S,Kubatzky K,Taromi S,Burger M,Orth J,Aktories K,Schmidt G
Fri Mar 30 00:00:00 EDT 2012
TGF-β-operated growth inhibition and translineage commitment into smooth muscle cells of periodontal ligament-derived endothelial progenitor cells through Smad- and p38 MAPK-dependent signals.
International journal of biological sciences
Yoshida M,Okubo N,Chosa N,Hasegawa T,Ibi M,Kamo M,Kyakumoto S,Ishisaki A
Wed Nov 28 00:00:00 EST 2012
Crosstalk between nuclear factor I-C and transforming growth factor-β1 signaling regulates odontoblast differentiation and homeostasis.
PloS one
Lee DS,Yoon WJ,Cho ES,Kim HJ,Gronostajski RM,Cho MI,Park JC
Mon Aug 27 00:00:00 EDT 2012
Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation.
The Journal of clinical investigation
Luna-Zurita L,Prados B,Grego-Bessa J,Luxán G,del Monte G,Benguría A,Adams RH,Pérez-Pomares JM,de la Pompa JL
Fri Oct 01 00:00:00 EDT 2010
GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells.
Proceedings of the National Academy of Sciences of the United States of America
Tran DQ,Andersson J,Wang R,Ramsey H,Unutmaz D,Shevach EM
Tue Aug 11 00:00:00 EDT 2009
Chronic NOS inhibition actuates endothelial-mesenchymal transformation.
American journal of physiology. Heart and circulatory physiology
O'Riordan E,Mendelev N,Patschan S,Patschan D,Eskander J,Cohen-Gould L,Chander P,Goligorsky MS
Mon Jan 01 00:00:00 EST 2007