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Product Details
210-17D-100UG
Applications
Tested Dilution
Publications
Product Specifications
Species
Mouse
Expression System
E. coli
Amino acid sequence
AGALRTGRRP ARPRDCADRP EELLEQLYGR LAAGVLSAFH HTLQLGPREQ ARNASCPAGG RAADRRFRPP TNLRSVSPWA YRISYDPARF PRYLPEAYCL CRGCLTGLYG EEDFRFRSTP VFSPAVVLRR TAACAGGRSV YAEHYITIPV GCTCVPEPDK SADSANSSMD KLLLGPADRP AGR
Molecular weight
40.6 kDa
Class
Recombinant
Type
Protein
Purity
≥ 95% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration
<1 EU/µg
Activity
Determined by its ability to bind murine IL-17RB Fc Chimera in a functional ELISA.
Conjugate
Form
Lyophilized
Purification
purified
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient
Product Specific Information
Recombinant Murine IL-17D is a 40.6 kDa, disulfide-linked homodimer of two 183 amino acid, polypeptide chains.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Target Information
The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ30846; IL-3R; interleukin 27A; interleukin-17D
Gene Aliases: AI462269; IL-17D; Il27a
Entrez Gene ID: (Mouse) 239114
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