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          • Home
          • › Search Tool
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          • › Hs01127705_m1
          See other ROCK1 GE Assays ›
          Gene Symbol:
          ROCK1
          Gene Name:
          Rho associated coiled-coil containing protein kinase 1
          Gene Aliases:
          P160ROCK, ROCK-I
          Chromosome Location:
          Chr.18: 20949740 - 21111851 on Build GRCh38
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          Assay ID Hs01127705_m1
          Size
          Availability Made To Order
          Catalog # 4351372
          Price 435.00
          Your Price
          Online offer: 408.65
          408.65
          Check your price ›
          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details

          Gene Symbol: ROCK1
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_005406.2 NP_005397.1 25 - 26 3939 162
          XM_011526137.2 XP_011524439.1 14 - 15 2173 162
          GenBank mRNA BC113114.1 - 25 - 26 3014 7961989 162
          U43195.1 - 25 - 26 2998 162

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          More Information


          Updated Mapping Information

          This assay targets the same location as Clariom D transcript cluster(s) TC1800008219.hg.1
          This assay targets the same location as HTA transcript cluster(s) TC18000397.hg.1

          Set Membership:

          Ambion siRNA available Amplicon length greater than or equal to 101 Protein Kinase Mammalian Gene Collection Homo sapiens Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene ROCK1

          Panther Classification:

          Molecular Function -

          non-receptor serine/threonine protein kinase

          Gene Ontology Categories:

          Function(s) Process(es)

          apical constriction
          protein phosphorylation
          cellular component disassembly involved in execution phase of apoptosis
          smooth muscle contraction
          leukocyte cell-cell adhesion
          signal transduction
          I-kappaB kinase/NF-kappaB signaling
          Rho protein signal transduction
          negative regulation of angiogenesis
          membrane to membrane docking
          actin cytoskeleton organization
          regulation of cell adhesion
          cortical actin cytoskeleton organization
          bleb assembly
          negative regulation of protein binding
          regulation of actin cytoskeleton organization
          negative regulation of myosin-light-chain-phosphatase activity
          negative regulation of neuron apoptotic process
          regulation of keratinocyte differentiation
          vascular endothelial growth factor receptor signaling pathway
          ephrin receptor signaling pathway
          leukocyte migration
          leukocyte tethering or rolling
          myoblast migration
          regulation of stress fiber assembly
          regulation of focal adhesion assembly
          positive regulation of focal adhesion assembly
          establishment of protein localization to plasma membrane
          regulation of establishment of endothelial barrier
          negative regulation of bicellular tight junction assembly
          regulation of establishment of cell polarity
          regulation of cell motility
          protein kinase activity
          protein serine/threonine kinase activity
          protein binding
          ATP binding
          GTP-Rho binding
          metal ion binding

          MicroArray Probes:

          Affymetrix

          Array Name Probe IDs Targets Target Type
          Affymetrix Human Transcriptome Array 2.0 PSR18004070.hg.1 ENST00000399799.1 Ensembl
          Affymetrix Human Transcriptome Array 2.0 PSR18004070.hg.1 NM_005406.2 Refseq
          Affymetrix Human Transcriptome Array 2.0 PSR18004070.hg.1 TC18000397.hg.1 HTA TC
          Affymetrix Human Clariom D Assay PSR1800156128.hg.1 ENST00000399799.2 Ensembl
          Affymetrix Human Clariom D Assay PSR1800156128.hg.1 NM_005406.2 Refseq
          Affymetrix Human Clariom D Assay PSR1800156128.hg.1 TC1800008219.hg.1 Clariom D TC
          Affymetrix Human Clariom D Assay PSR1800156128.hg.1 ENST00000399799.2 Ensembl
          Affymetrix Human Clariom D Assay PSR1800156128.hg.1 NM_005406.2 Refseq

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