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          • Home
          • › Search Tool
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          • › Mm00434256_m1
          See other IL2 GE Assays ›
          Gene Symbol:
          Il2
          Gene Name:
          interleukin 2
          Gene Aliases:
          Il-2
          Chromosome Location:
          Chr.3: 37120713 - 37125954 on Build GRCm38
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          Assay ID Mm00434256_m1
          Best Coverage
          Size
          Availability Inventoried
          Catalog # 4331182
          Price 284.00
          Your Price
          Online offer: 266.65
          266.65
          Check your price ›
          • Genomic Map
          • Assay Details
          • More Information
          • Citations (3)

          Genomic Map

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          Assay Details

          Gene Symbol: Il2
          Interrogated Sequence Translated Protein Exon Boundary Assay Location IMAGE Clone ID Amplicon Length
          RefSeq NM_008366.3 NP_032392.1 2 - 3 296 82
          GenBank mRNA AF065914.1 - 2 - 3 294 82
          AF065915.1 - 2 - 3 294 82
          AF065916.1 - 2 - 3 294 82
          AY147902.1 - 2 - 3 248 82
          BC116845.1 - 2 - 3 294 40126164 82
          BC116873.1 - 2 - 3 294 40126192 82
          DQ836354.1 - 2 - 3 188 82
          K02292.1 - 2 - 3 296 82
          U41494.1 - 2 - 3 191 82
          U41504.1 - 2 - 3 206 82
          U41505.1 - 2 - 3 218 82
          U41506.1 - 2 - 3 191 82
          X01772.1 - 2 - 3 295 82
          X73040.1 - 2 - 3 295 82

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          More Information


          Updated Mapping Information

          This assay targets the same location as MTA transcript cluster(s) TC0300001864.mm.1

          Set Membership:

          Ambion siRNA available Amplicon length between 71 and 85 Mammalian Gene Collection Recommended Assay Mus musculus Mouse Chemokine Panel Mouse Tumor Metastasis Panel Mouse Immune Response Inventoried Mouse_Immune_Response Probe spans exons

          Matching Ambion siRNAs:

          Click here to find siRNAs for Gene Il2

          Panther Classification:

          Molecular Function -

          actin or actin-binding cytoskeletal protein non-receptor serine/threonine protein kinase

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of protein phosphorylation
          positive regulation of protein phosphorylation
          immune system process
          negative regulation of B cell apoptotic process
          immune response
          G-protein coupled receptor signaling pathway
          positive regulation of cytosolic calcium ion concentration
          protein kinase C-activating G-protein coupled receptor signaling pathway
          positive regulation of B cell proliferation
          positive regulation of interferon-gamma production
          positive regulation of interleukin-17 production
          positive regulation of T cell proliferation
          positive regulation of activated T cell proliferation
          positive regulation of tyrosine phosphorylation of Stat5 protein
          positive regulation of T cell differentiation
          positive regulation of regulatory T cell differentiation
          negative regulation of heart contraction
          positive regulation of transcription from RNA polymerase II promoter
          regulation of T cell homeostatic proliferation
          positive regulation of isotype switching to IgG isotypes
          negative regulation of lymphocyte proliferation
          negative regulation of inflammatory response
          positive regulation of immunoglobulin secretion
          positive regulation of dendritic spine development
          extrinsic apoptotic signaling pathway in absence of ligand
          cytokine activity
          interleukin-2 receptor binding
          growth factor activity
          carbohydrate binding
          kappa-type opioid receptor binding
          glycosphingolipid binding

          MicroArray Probes:

          Affymetrix

          Array Name Probe IDs Targets Target Type
          Affymetrix Mouse Clariom S Array PSR0300014436.mm.1 NM_008366.3.1 Refseq
          Affymetrix Mouse Clariom S Array PSR0300014436.mm.1 NM_008366.3 Refseq
          Affymetrix Mouse Clariom S Array PSR0300014436.mm.1 TC0300001864.mm.1 MTA TC

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          Citations (3)

          The effects of targeted deletion of cannabinoid receptors CB1 and CB2 on intranasal sensitization and challenge with adjuvant-free ovalbumin.
          Authors
          Kaplan BL, Lawver JE, Karmaus PW, Ngaotepprutaram T, Birmingham NP, Harkema JR, Kaminski NE
          Journal
          Toxicol Pathol - Page No 382 (Fri Jan 01 00:00:00 EST 2010)
          Volume (Year)
          38 (2010)
          Product Usage
          -
          Early rise in inflammation and microcirculatory disorder determine the development of autoimmune pancreatitis in the MRL/Mp-mouse.
          Authors
          Sorg H, Lorch B, Jaster R, Fitzner B, Ibrahim S, Holzhueter SA, Nizze H, Vollmar B
          Journal
          Am J Physiol Gastrointest Liver Physiol - Page No G1274 (Mon Dec 01 00:00:00 EST 2008)
          Volume (Year)
          295 (2008)
          Product Usage
          -
          TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells.
          Authors
          Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B
          Journal
          Immunity - Page No 179 (Wed Feb 01 00:00:00 EST 2006)
          Volume (Year)
          24 (2006)
          Product Usage
          -

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