The Transforming Growth Factors (TGFs) are multifunctional peptides that regulate growth and differentiation in a variety of cells. Recent data suggests that individual TGF-beta isoforms (TGF-beta1, -beta2 and -beta3) have overlapping, yet distinct biological actions and target cell specificities, both in developing and adult tissues. TGF-beta3 is a new isoform that is presumed to play an important role in wound repair and scarring. TGF-beta3 is also thought to be involved in osteoblast proliferation, chemotaxis, and collagen synthesis.
ARVD; FLJ16571; prepro-transforming growth factor beta-3; TGF-beta-3; TGF-beta3; Transforming growth factor beta-3; transforming growth factor, beta 3
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