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Invitrogen
GTDC1 Polyclonal Antibody
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Product Details
PA5-57774
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GTDC1. Recombinant protein control fragment (Product #RP-96058).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: HWGYLPSKDD YFQVLCMADV VISTAKHEFF GVAMLEAVYC GCYPLCPKDL VYPEIFPAEY LYSTPEQLSK RLQNFCKRPD IIRKHLYKGE IAPFSWAAL
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.
Target Information
The GTDC1 (Glycosyltransferase-Like Domain Containing 1) gene encodes a protein that is hypothesized to function as a glycosyltransferase. This gene has been implicated in several crucial biological processes, particularly in the nervous system. The GTDC1 cDNA is 2954 base pairs in length, encoding a protein of 458 amino acids, and shows high expression in tissues such as the lung, spleen, testis, and peripheral blood leukocytes. Genetic studies have highlighted its potential role in developmental disorders, such as global developmental delay and delayed speech and language development, linked to microdeletions encompassing the GTDC1 gene. Disruption of GTDC1 expression has been shown to affect neural progenitor cells and neurons, indicating its significance in neural development. Additionally, the gene holds evolutionary conservation, sharing 75% and 37% identity with its mouse and fruit fly counterparts, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: glycosyltransferase-like 1; glycosyltransferase-like domain containing 1; Glycosyltransferase-like domain-containing protein 1; mannosyltransferase candidate; Mannosyltransferase-like protein Xa; Mat-Xa; QTMAN; tRNA-queuosine alpha-mannosyltransferase
Gene Aliases: GTDC1; Hmat-Xa; mat-Xa; QTMAN
UniProt ID: (Human) Q53SM7
Entrez Gene ID: (Human) 79712
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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