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PrepSEQ Sample Preparation Kits

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PrepSEQ Sample Preparation Kits for Bioprocessing Analytics

PrepSEQ sample preparation kits offer flexible, magnetic bead-based nucleic acid purification for contaminant and impurity testing workflows. Designed for complex bioprocessing samples, the PrepSEQ portfolio supports manual, cartridge-based, and automated sample preparation across multiple applications.

Compare PrepSEQ kits

Workflow Recommended PrepSEQ kit

Residual host cell DNA quantitation

PrepSEQ Residual DNA Sample Preparation Kit

Broad DNA/RNA purification

PrepSEQ Nucleic Acid Sample Preparation Kit

Mycoplasma detection

PrepSEQ 1-2-3 or PrepSEQ 1-2-3 Mycoplasma or PrepSEQ Express

MMV detection

PrepSEQ 1-2-3 or PrepSEQ Express

Vesivirus detection

PrepSEQ 1-2-3 or PrepSEQ Express

PrepSEQ Residual DNA Sample Preparation Kit

For residual host-cell DNA workflows, the PrepSEQ Residual DNA Sample Preparation Kit helps recover DNA from complex bioprocessing samples that may contain proteins, buffers, salts, or other components that can make extraction more challenging.

 

This kit is a strong fit when your workflow involves residual DNA quantitation from samples generated during biologics development or manufacturing.

Consider this kit when:

  • You are preparing samples for residual host-cell DNA quantitation
  • Your sample matrix is complex or process-derived
  • Your samples may contain high protein, high salt, low pH, or low DNA concentration
  • You need consistent DNA recovery before qPCR analysis
  • You want to automate residual DNA sample preparation, where supported by your workflow

Common workflow fit: Residual host-cell DNA quantitation, bioprocessing impurity testing, and in-process or final product testing workflows, where applicable

 

Related automation: Automation depends on the specific workflow and protocol. Use the platform comparison page to evaluate whether AutoMate Express systems, KingFisher systems, or a manual workflow is the best fit.

PrepSEQ Nucleic Acid Sample Preparation Kit

The PrepSEQ Nucleic Acid Sample Preparation Kit is designed for DNA and RNA extraction from diverse bioprocessing sample types. It can support workflows where nucleic acid recovery is needed from cell culture, raw material, in-process, or downstream purification samples.

 

This kit is a good fit when your testing need is broader than residual DNA alone and the workflow requires recovery of DNA or RNA from varied sample matrices.

Consider this kit when:

  • You need to recover DNA and/or RNA from diverse bioprocessing samples
  • Your samples come from different points in the bioproduction workflow
  • You are preparing samples for viral nucleic acid detection or quantitation workflows, where applicable
  • You need a workflow that can support complex sample matrices
  • You want to scale nucleic acid sample preparation using compatible automation

Common workflow fit: Nucleic acid recovery from complex samples, viral DNA or RNA sample preparation where applicable, and bioprocessing contaminant testing workflows

 

Related automation: Automation depends on the specific workflow and protocol. Use the platform comparison page to evaluate whether AutoMate Express systems, KingFisher systems, or a manual workflow is the best fit.

PrepSEQ 1-2-3 Nucleic Acid Extraction Kit

The PrepSEQ 1-2-3 Nucleic Acid Extraction Kit uses magnetic particle-based separation technology for nucleic acid extraction in contaminant testing workflows. It is commonly associated with mycoplasma, MMV, and vesivirus sample preparation applications.
 

This kit is a strong fit when your workflow requires magnetic particle-based extraction before downstream PCR-based contaminant testing.

Consider this kit when:

  • You are preparing samples for mycoplasma detection
  • You are preparing samples for MMV or Vesivirus detection
  • You need magnetic particle-based nucleic acid extraction
  • Your workflow uses established PrepSEQ 1-2-3 protocols
  • You need a sample prep approach for contaminant testing workflows

Common workflow fit: Mycoplasma detection, MMV detection, vesivirus detection, and contaminant testing sample preparation

 

Related automation: Automation depends on the specific workflow and protocol. Use the platform comparison page to evaluate whether AutoMate Express, KingFisher systems, or a manual workflow is the best fit.

PrepSEQ 1-2-3 Mycoplasma Nucleic Acid Extraction Kit

The PrepSEQ 1-2-3 Mycoplasma Nucleic Acid Extraction Kit is designed for rapid extraction of Mycoplasma genomic DNA from mammalian cell culture samples. The kit uses magnetic bead-based separation and is optimized for use with the MycoSEQ Mycoplasma Detection Kit.
 

This kit is a strong fit when the lab wants a rapid, streamlined sample-preparation workflow for routine Mycoplasma testing of cell culture and cell therapy samples.

Consider this kit when:

  • You are using or evaluating the MycoSEQ Mycoplasma Detection Kit
  • You want magnetic bead-based DNA extraction
  • You are testing research, stem cell, or cell therapy samples
  • You want high recovery of Mycoplasma genomic DNA
  • You want a rapid workflow suitable for routine Mycoplasma screening

Common workflow fit: Mycoplasma screening of mammalian cell cultures, stem cell cultures, and cellular or tissue therapy samples.
 

Related detection assay: MycoSEQ Mycoplasma Detection Kit.
 

Related automation: Automation depends on the specific workflow and protocol. Use the platform comparison page to evaluate whether AutoMate Express, KingFisher systems, or a manual workflow is the best fit.

PrepSEQ Express Nucleic Acid Extraction Kit

The PrepSEQ Express Nucleic Acid Extraction Kit is designed for use with the AutoMate Express system. The kit uses prefilled cartridges and workflow plastics to support automated extraction of DNA and/or RNA from mycoplasma cells or viral particles.

 

This kit is a strong fit when the lab wants a closed, ready-to-run, cartridge-based automation format for defined contaminant testing workflows.

Consider this kit when:

  • You are using or evaluating the AutoMate Express system
  • You want prefilled reagent cartridges
  • You want a closed, hands-free extraction workflow
  • You are preparing samples for mycoplasma, MMV, or vesivirus detection workflows
  • You want to reduce manual handling in defined contaminant testing workflows

Common workflow fit: Mycoplasma detection, MMV detection, vesivirus detection, and combined contaminant surveillance workflows, where applicable


Related automation: AutoMate Express systems

Ready to automate your PrepSEQ workflow?

Once you've selected the appropriate PrepSEQ chemistry, choose the automation platform that best fits your laboratory.

Analytics Knowledge Hub


Explore the Analytics Knowledge Hub and discover a robust collection of webinars, articles, eBooks, infographics, and other digital resources to help you optimize analytical testing in your bioprocess workflow.
 

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No matter your questions, we are here to help. Our experienced team of scientists and technical specialists is ready to assist you in choosing the right solution and products. Complete this form to start the conversation.
 

 

For Research Use Only. Not for use in diagnostic procedures.