Case Study

Secondary Complications Due to Unnecessary Antibiotic Use


Valerie Vaughn, MD MSc
Assistant Professor
Director of Hospital Medicine Research



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Key Takeaways

Takeaway #1

Takeaway #1

Antibiotic therapy can cause superinfection with C. difficile that can result in life-threatening side effects



Takeaway #2

Takeaway #2

Early PCT determination could have decreased the time on antibiotics as it has a high NPV for bacterial infection.



Takeaway #3

Takeaway #3

PCT has a high predictive value for negative blood cultures with a much shorter TAT than the blood culture itself.



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