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A breakthrough in monoclonal​ gammopathy assessment

The EXENT® System is an automated solution that enables M-protein identification and measurement in serum with enhanced sensitivity beyond conventional methods

The EXENT System is the latest innovative solution from the Binding Site, part of Thermo Fisher Scientific​

​The system combines the EXENT Analyser with the EXENT GAM Assay* to provide a fully automated solution to isotype, quantify and track monoclonal proteins throughout the patient journey.​

​The EXENT System is a regulatory compliant and easy to implement solution for routine laboratory use​.

What is the EXENT System?​

The EXENT System integrates immunoassay, MALDI-ToF mass spectrometry and intuitive data review software to provide enhanced analytical sensitivity and specificity for the measurement of monoclonal proteins. The analyzer has been designed to specifically address workflow and interpretation challenges faced by the clinical laboratory.

Watch this short video to see the EXENT System in action!
Watch video (01:58)

The EXENT Analyser consists of three integrated modules:​

Primary serum sample to mass spectrometry ready

Immunoassay automatically isolates immunoglobulins using isotype-specific paramagnetic reagents

How does the EXENT System prepare the samples?
Watch the video now

Rapidly analyze samples using MALDI-ToF mass spectrometry with load & click technology​

Integrated calibration and control routines are combined with automated sample measurement to remove the need for mass spectrometry expertise

How does the EXENT System analyze samples?
Watch the video now

Easily review & release results using an intuitive data analysis software

Automated peak picking and the ability to specifically track monoclonal proteins using their molecular mass reduces complexity and subjectivity when reviewing results​

Discover more about the EXENT System

EXENT GAM Assay
Immunoassays
EXENT GAM Assay
The EXENT Analyser with the EXENT GAM Assay provides a sensitive and specific method for the assessment of M-proteins in patients with monoclonal gammopathies.
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Product availability is subject to country specific regulatory requirements. Contact your local representative for availability in your country.
This product is not commercially available in the USA or China. Future commercial availability cannot be guaranteed.
EXENT and Optilite are registered trademarks of The Binding Site Group Limited (Birmingham, UK) in certain countries.
The EXENT® System combines EXENT® Analyser with Immunoglobulin Isotypes (GAM) for the EXENT® Analyser.
*EXENT GAM Assay refers to Immunoglobulin Isotypes (GAM) for the EXENT® Analyser.
 
The EXENT® System consists of the following CE marked products:
  • EXENT Analyser, IE800 (IVDR Class A, nonsterile);
  • Immunoglobulin isotypes (GAM) for the EXENT Analyser - MSR801.M (IVDR Class C),
  • EXENT Immunoglobulin Isotypes (GAM) Control Pack - MSQ801.M (IVDR Class C).
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