A breakthrough in monoclonal​ gammopathy assessment

The EXENT® System is an automated solution that enables M-protein identification and measurement in serum with enhanced sensitivity

The EXENT System is the latest innovative solution from the Binding Site, part of Thermo Fisher Scientific​

​The system combines the EXENT Analyser with the EXENT GAM Assay* to provide a fully automated solution to isotype and measure monoclonal proteins.

​The EXENT System is a 510(k) cleared and easy to implement solution for routine laboratory use.

Experience the EXENT® System

Learn more about the EXENT System in the video below:

Watch this short video (01:58) to see the EXENT System in action!

 

 

What is the EXENT System?​

The EXENT System integrates immunoassay, MALDI-ToF mass spectrometry and intuitive data review software to provide enhanced sensitivity and specificity for the measurement of monoclonal proteins. The analyzer has been designed to specifically address workflow and interpretation challenges faced by the clinical laboratory.

The EXENT Analyser consists of three integrated modules:​


Prepare

Automatically isolate immunoglobulins using isotype-specific paramagnetic reagents

Analyze

Rapidly analyze samples by MALDI-ToF mass spectrometry with load & click technology

Data Review

Automatically isolate immunoglobulins using isotype-specific paramagnetic reagents

Rapidly analyze samples by MALDI-ToF mass spectrometry with load & click technology

Easily review & release results using a simple intuitive interface

Integration for measurement

Optilite® Analyser*

*Optilite® Analyser is not part of the EXENT® Analyser


Primary serum sample to mass spectrometry ready

Immunoassay automatically isolates immunoglobulins using isotype-specific paramagnetic reagents


How does the EXENT System prepare the samples?

Rapidly analyze samples using MALDI-ToF mass spectrometry with load & click technology​

Integrated calibration and control routines are combined with automated sample measurement to remove the need for mass spectrometry expertise


How does the EXENT System analyze samples?

Easily review & release results using an intuitive data analysis software

Automated peak picking reduces complexity and subjectivity when reviewing results​

EXENT System connectivity

The EXENT System is provided with ASTM connectivity

  • Ordering
  • Released Optilite® result
  • Ordering
  • Released result
  • Released result
  • Released result
  • Ordering
  • Released Optilite assay result
  • Released result
  • Ordering

 

Unified patient test ordering


Unified patient test ordering

 

Automatic data transfer of Optilite assay results to the EXENT Analyser


Automatic data transfer of Optilite assay results to the EXENT Analyser

 

Automatic upload of released EXENT assay results


Automatic upload of released EXENT assay results

Related content

EXENT GAM Assay

The EXENT Analyser with the EXENT GAM Assay provides a sensitive and specific method for the assessment of M-proteins in patients with monoclonal gammopathies.

This product is not commercially available in China. Future commercial availability cannot be guaranteed.
EXENT and Optilite are registered trademarks of The Binding Site Group Limited (Birmingham, UK) in certain countries.
The EXENT® System combines EXENT® Analyser with Immunoglobulin Isotypes (GAM) for the EXENT® Analyser.
*EXENT GAM Assay refers to Immunoglobulin Isotypes (GAM) for the EXENT® Analyser.
 
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