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          • Home
          • › Search Tool
          • › Search Results
          • › Hs05919225_cn
          See other NFKB1 CNV Assays ›
          Gene Symbol
          NFKB1
          Assay Reference Genome
          Location

          Chr.4:102553044 on build GRCh38
          Cytoband
          4q24
          Assay ID Hs05919225_cn
          Size
          Availability Made To Order
          Catalog # 4400291
          Price
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          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details

          Target Gene Details

          Entrez Gene ID:

          4790

          Gene Name:

          nuclear factor kappa B subunit 1

          Gene Aliases:

          CVID12, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50

          Location:

          Chr.4:102501329-102617302 on Build GRCh38

          Assay Gene Location:

          Within Intron 7
          Gene Symbol Transcript Accession Exon Location Assay Transcript Location Protein ID
          NFKB1 NM_001165412.1 NP_001158884.1
          NM_001319226.1 NP_001306155.1
          NM_003998.3 NP_003989.2
          XM_011532006.2 XP_011530308.1
          XM_011532008.2 XP_011530310.1
          AK291450.1
          BC051765.1 AAH51765.1
          CR749522.1 CAH18336.1
          M55643.1 AAA36361.1
          M58603.1 AAA36360.1

          Target Copy Number Variation Details

          DGV Version:

          Release date: 2016-05-15, GRCh GRCh38
          Target
          Variation
          Location CNV
          Subtype
          Genes
          nsv830020 Chr.4:102466186 - 102660127 on Build GRCh38 Loss NFKB1 LOC105377621 MANBA

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          More Information


          Set Membership:

          Intragenic Intronic Non-exonic DGV Variation

          Panther Classification:

          Molecular Function -

          Rel homology transcription factor

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          stimulatory C-type lectin receptor signaling pathway
          transcription from RNA polymerase II promoter
          apoptotic process
          inflammatory response
          response to oxidative stress
          I-kappaB kinase/NF-kappaB signaling
          positive regulation of macrophage derived foam cell differentiation
          positive regulation of lipid storage
          negative regulation of calcidiol 1-monooxygenase activity
          negative regulation of vitamin D biosynthetic process
          membrane protein intracellular domain proteolysis
          negative regulation of cellular protein metabolic process
          negative regulation of cholesterol transport
          positive regulation of type I interferon production
          response to muscle stretch
          NIK/NF-kappaB signaling
          Fc-epsilon receptor signaling pathway
          negative regulation of apoptotic process
          negative regulation of interleukin-12 biosynthetic process
          innate immune response
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          response to copper ion
          negative regulation of inflammatory response
          T cell receptor signaling pathway
          positive regulation of NF-kappaB transcription factor activity
          stress-activated MAPK cascade
          cellular response to lipopolysaccharide
          cellular response to mechanical stimulus
          cellular response to nicotine
          cellular response to carbohydrate stimulus
          cellular response to interleukin-1
          cellular response to interleukin-6
          cellular response to tumor necrosis factor
          cellular response to dsRNA
          cellular response to peptide hormone stimulus
          positive regulation of canonical Wnt signaling pathway
          positive regulation of hyaluronan biosynthetic process
          cellular response to diterpene
          cellular response to glucoside
          cellular response to brain-derived neurotrophic factor stimulus
          positive regulation of miRNA metabolic process
          regulatory region DNA binding
          transcription regulatory region sequence-specific DNA binding
          RNA polymerase II regulatory region sequence-specific DNA binding
          RNA polymerase II distal enhancer sequence-specific DNA binding
          transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
          transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
          chromatin binding
          transcription factor activity, sequence-specific DNA binding
          protein binding
          transcription factor binding
          heat shock protein binding
          identical protein binding
          protein homodimerization activity
          actinin binding
          transcription regulatory region DNA binding
          protein heterodimerization activity

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