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          • Home
          • › Search Tool
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          • › Hs06194514_cn
          See other PTK2B CNV Assays ›
          Gene Symbol
          PTK2B
          Assay Reference Genome
          Location

          Chr.8:27379586 on build GRCh38
          Cytoband
          8p21.2
          Assay ID Hs06194514_cn
          Size
          Availability Made To Order
          Catalog # 4400291
          Price
          Your Price
          Online offer:
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          • Genomic Map
          • Assay Details
          • More Information

          Genomic Map

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          Assay Details

          Target Gene Details

          Entrez Gene ID:

          2185

          Gene Name:

          protein tyrosine kinase 2 beta

          Gene Aliases:

          CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK

          Location:

          Chr.8:27311482-27459391 on Build GRCh38

          Assay Gene Location:

          Within Intron 8
          Gene Symbol Transcript Accession Exon Location Assay Transcript Location Protein ID
          PTK2B NM_004103.4 NP_004094.3
          NM_173174.2 NP_775266.1
          NM_173175.2 NP_775267.1
          NM_173176.2 NP_775268.1
          XM_005273448.4 XP_005273505.1
          XM_011544441.2 XP_011542743.1
          XM_011544442.2 XP_011542744.1
          XM_017013214.1 XP_016868703.1
          XM_017013215.1 XP_016868704.1
          XM_017013216.1 XP_016868705.1
          AB209085.1 BAD92322.1
          BC036651.2 AAH36651.1
          BC042599.2 AAH42599.1
          BF796371.1
          D45853.1 BAA08289.1
          DA773624.1
          L49207.1 AAB47217.1
          U33284.1 AAC50203.1
          U43522.1 AAC05330.1

          Target Copy Number Variation Details

          DGV Version:

          Release date: 2016-05-15, GRCh GRCh38
          Target
          Variation
          Location CNV
          Subtype
          Genes
          esv3616721 Chr.8:27375902 - 27443884 on Build GRCh38 Gain MIR6842 PTK2B

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          More Information


          Set Membership:

          Intragenic Intronic Non-exonic DGV Variation

          Gene Ontology Categories:

          Function(s) Process(es)

          MAPK cascade
          angiogenesis
          oocyte maturation
          response to hypoxia
          positive regulation of cell-matrix adhesion
          sprouting angiogenesis
          adaptive immune response
          marginal zone B cell differentiation
          protein complex assembly
          protein phosphorylation
          apoptotic process
          response to stress
          cellular defense response
          response to osmotic stress
          signal transduction
          cell surface receptor signaling pathway
          signal complex assembly
          epidermal growth factor receptor signaling pathway
          positive regulation of cytosolic calcium ion concentration
          integrin-mediated signaling pathway
          positive regulation of cell proliferation
          negative regulation of cell proliferation
          regulation of cell shape
          response to mechanical stimulus
          response to hormone
          response to glucose
          response to lithium ion
          positive regulation of endothelial cell migration
          negative regulation of muscle cell apoptotic process
          regulation of cGMP-mediated signaling
          regulation of macrophage chemotaxis
          positive regulation of neuron projection development
          glial cell proliferation
          peptidyl-tyrosine phosphorylation
          regulation of cell adhesion
          positive regulation of cell growth
          positive regulation of cell migration
          negative regulation of bone mineralization
          regulation of cGMP biosynthetic process
          positive regulation of actin filament polymerization
          neuron projection development
          regulation of inositol trisphosphate biosynthetic process
          tumor necrosis factor-mediated signaling pathway
          ionotropic glutamate receptor signaling pathway
          response to immobilization stress
          peptidyl-tyrosine autophosphorylation
          response to cocaine
          response to drug
          response to hydrogen peroxide
          activation of Janus kinase activity
          negative regulation of apoptotic process
          stress fiber assembly
          negative regulation of potassium ion transport
          positive regulation of JUN kinase activity
          negative regulation of neuron apoptotic process
          blood vessel endothelial cell migration
          positive regulation of phosphatidylinositol 3-kinase activity
          innate immune response
          positive regulation of nitric oxide biosynthetic process
          bone resorption
          response to ethanol
          negative regulation of myeloid cell differentiation
          positive regulation of translation
          positive regulation of angiogenesis
          positive regulation of protein kinase activity
          positive regulation of JNK cascade
          protein autophosphorylation
          vascular endothelial growth factor receptor signaling pathway
          focal adhesion assembly
          positive regulation of peptidyl-tyrosine phosphorylation
          regulation of calcium-mediated signaling
          positive regulation of nitric-oxide synthase activity
          regulation of release of sequestered calcium ion into cytosol
          response to cAMP
          response to calcium ion
          positive regulation of synaptic transmission, glutamatergic
          long-term synaptic potentiation
          long term synaptic depression
          chemokine-mediated signaling pathway
          positive regulation of ERK1 and ERK2 cascade
          cellular response to retinoic acid
          cellular response to fluid shear stress
          activation of GTPase activity
          regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
          positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
          regulation of establishment of cell polarity
          regulation of actin cytoskeleton reorganization
          regulation of N-methyl-D-aspartate selective glutamate receptor activity
          positive regulation of excitatory postsynaptic potential
          positive regulation of B cell chemotaxis
          positive regulation of DNA biosynthetic process
          calmodulin-dependent protein kinase activity
          protein tyrosine kinase activity
          non-membrane spanning protein tyrosine kinase activity
          signal transducer activity
          NMDA glutamate receptor activity
          receptor binding
          protein binding
          ATP binding
          protein complex binding
          3-phosphoinositide-dependent protein kinase binding

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