Thermo Scientific™

DMP (dimethyl pimelimidate)

Catalog number:  21666

Related applications:

Protein Labeling & Crosslinking

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Description

Thermo Scientific Pierce DMP is dimethyl pimelimidate, a membrane-permeable crosslinker that contains an amine-reactive imidoester group at each end of a 7-atom spacer arm.

Features of dimethyl pimelimidate:

Reactive groups: imidoester (both ends)
Reactive towards: amino groups (primary amines)
• Mid-length reagent of three similar imidoester crosslinkers, which include DMA, DMP and DMS
• Water-soluble
• Imidoesters react with amines at alkaline pH values (pH 8-10) to form amidine bond
• Amidine bond retains net charge character of protein primary amine to which it reacts
• Reversible at high pH values
• Tool for study of quarternary structure of proteins

Product References
Crosslinker Application Guide -- search for recent literature references for this product

Related Products
DMA (dimethyl adipimidate)
DMS (dimethyl suberimidate)
DTBP (Wang and Richard's Reagent)
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Product Line: Pierce™
Crosslinker Type: Homobifunctional
Labeling Method: Chemical Labeling
Reactive Moiety: Imidoester
Solubility: Water
Spacer: Short
Quantity: 50mg

Contents & storage

Store desiccated at 4°C. Shipped at ambient temperature.