Thermo Scientific™

DMS (dimethyl suberimidate)

Catalog number: 20700
Thermo Scientific™

DMS (dimethyl suberimidate)

Catalog number: 20700
Catalog Number
20700
Unit Size
1 g
Price (USD)
Price: 183.00
Your price:
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
207001 g
Price: 183.00
Your price:
-
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Thermo Scientific Pierce DMS is dimethyl suberimidate, a membrane-permeable crosslinker that contains an amine-reactive imidoester group at each end of an 8-atom spacer arm.

Features of dimethyl suberimidate:

Reactive groups: imidoester (both ends)
Reactive towards: amino groups (primary amines)
• Longest of three similar imidoester crosslinkers, which include DMA, DMP and DMS
• Water-soluble
• Imidoesters react with amines at alkaline pH values (pH 8-10) to form amidine bond
• Amidine bond retains net charge character of protein primary amine to which it reacts
• Reversible at high pH values
• Tool for study of quarternary structure of proteins

Product References
Crosslinker Application Guide -- search for recent literature references for this product

Related Products
DMA (dimethyl adipimidate)
DMP (dimethyl pimelimidate)
DTBP (Wang and Richard's Reagent)
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Chemical Reactivity
Amine-Amine
Cleavable
No
Description
DMS
Molecular Weight (g/mol)
273.2
PEGylated
No
Spacer Arm Length
11.0 Å
Cell Permeability
Yes
Shipping Condition
Ambient
Product Line
Pierce™
Labeling Method
Chemical Labeling
Crosslinker Type
Homobifunctional
Reactive Moiety
Imidoester
Spacer
Medium (10 to 30 Å)
Form
Powder
Quantity
1 g
Solubility
Water
Format
Standard
Water Soluble
Yes
Product Type
Crosslinker

Contents & Storage

Upon receipt store desiccated at 4°C.

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