2'-Fluoro-iBu-G Phosphoramidite, standard grade, 28-400 finish bottle
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2'-Fluoro-iBu-G Phosphoramidite, standard grade, 28-400 finish bottle
Thermo Scientific™

2'-Fluoro-iBu-G Phosphoramidite, standard grade, 28-400 finish bottle

2'-Fluoro-iBu-G CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with 2'-Fluoro protection, for use in oligonucleotideRead more
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Catalog number 27-1607-12
Price (USD)/ 0.5 g
45.68
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Add to cart
Price (USD)/ 0.5 g
45.68
Add to cart
2'-Fluoro-iBu-G Phosphoramidite, standard grade, 28-400 finish bottle
Catalog number27-1607-12
Price (USD)/ 0.5 g
45.68
-
Add to cart

2'-Fluoro-iBu-G CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with 2'-Fluoro protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, the highly electronegative fluorine (2'-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2'-OH), the 2'-F modification has been proven useful in antisense, siRNA, and aptamer applications. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 30-mL amber bottle with a 28-400 finish neck style, which is compatible with most MerMade synthesizers.

Features:
• Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-fluoroguanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula—C44H53FN7O8P
• Base—G
• Base Protection—iBu
• Formula weight—857.4 g/mol
• CAS number—144089-97-4
• HPLC purity—>98%
31P NMR purity—≥98%

For Research Use Only. Not for use in diagnostic procedures.
Specifications
For Use With (Equipment)MerMade Synthesizers
Product Type2in-Fluoro-iBu-G CEP
Nucleoside TypeGuanosine (G)
Reagent Features2in-Fluoro modified
Shipping ConditionRoom Temperature
Purity98%
Quantity0.5 g
Reagent TypePhosphoramidite
GradeStandard
Nucleic Acid TypeRNA
FormPowder
Unit Size0.5 g
Contents & Storage
Store in freezer (at or below -20°C).