Thermo Scientific™

Pharma mini HME Micro Compounder

Catalog number: 553-6050
Thermo Scientific™

Pharma mini HME Micro Compounder

Catalog number: 553-6050
The Thermo Scientific™ Pharma mini HME is a GMP compliant conical micro compounder for Hot Melt Extrusion in research and development in the pharmaceutical industry. When developing new drugs, shortening time-to-market and reducing waste of expensive API's and overall development costs provide a distinct competitive advantage. Hence, quick and early assessment of new API/excipient formulations is critical. Hot melt extrusion and continuous processing can lead to speedier formulation development and cost efficient production. The Thermo Scientific Pharma mini HME allows users to identify the right drug candidates for hot melt extrusion by compounding as little as three grams of material.
 
Catalog Number
553-6050
Unit Size
Each
Barrel
High performance / pharma grade stainless steel M340
Description
Pharma mini HME base unit
Max. Screw Speed
co- and counter-rotating screws
Price (USD)
Full specifications
Feed Zones1
Max. Temperature280°C
BarrelHigh performance / pharma grade stainless steel M340
Hertz50/60Hz
Screw TypeCo- or counter rotating, pharma grade stainless steel 1.4112 (440 B)
Speed10 to 360 min¹
Temperature (Metric) OperatingMax. 280°C with 2 set points
Max. Motor Power400w
DescriptionPharma mini HME base unit
Voltage115V ±10%, 230V ±10%
Max. Torque5 Nm / shaft
Volume (Metric)4 mL
Max. Volume4 ml
Min. Sample Weight3 g
Drive Power400 W
Electrical Requirements115V ±10%, 230V ±10% 50/60Hz
Max. Screw Speedco- and counter-rotating screws
Unit SizeEach
Showing 1 of 1
Catalog NumberSpecificationsUnit SizeBarrelDescriptionMax. Screw SpeedPrice (USD)
553-6050Full specifications
EachHigh performance / pharma grade stainless steel M340Pharma mini HME base unitco- and counter-rotating screwsRequest A Quote
Feed Zones1
Max. Temperature280°C
BarrelHigh performance / pharma grade stainless steel M340
Hertz50/60Hz
Screw TypeCo- or counter rotating, pharma grade stainless steel 1.4112 (440 B)
Speed10 to 360 min¹
Temperature (Metric) OperatingMax. 280°C with 2 set points
Max. Motor Power400w
DescriptionPharma mini HME base unit
Voltage115V ±10%, 230V ±10%
Max. Torque5 Nm / shaft
Volume (Metric)4 mL
Max. Volume4 ml
Min. Sample Weight3 g
Drive Power400 W
Electrical Requirements115V ±10%, 230V ±10% 50/60Hz
Max. Screw Speedco- and counter-rotating screws
Unit SizeEach
Showing 1 of 1
With the Pharma mini HME, we offer a micro twin-screw compounder which requires as little as three grams of total material to identify the right drug candidates for hot melt extrusion. The compounder with conical co- or counter-rotating screws is designed to minimize waste and reduce downtime necessary for cleaning.
  • Requires only 3g (4mL) of material for compounding
  • Small footprint, fanless design with separate, touch-screen control for operation in fume cabinet or glovebox applications
  • Removable and exchangeable product contact parts for quick and easy cleaning
  • IP 54 for protection against dust and water allows the Pharma mini HME to be spray-washed
  • Useable as small-scale production unit for throughputs of 100g/h
  • Touch screen control with user levels and password protection
  • Data logging software as option to record temperatures, torque, and screw speed
  • Optional batch conversion kit to use the Pharma mini HME as small batch mixer
  • Complementary workflow solution when coupled with the Thermo Scientific™ HAAKE™ MiniJet injection molder

Recommended for:

Materials:

  • Pharmaceutical ingredients (API's)
  • Excipients
  • Medical polymers
  • Drug delivery systems
  • Soft gels

Applications:

  • Hot melt extrusion
  • Medical devices
  • Implants
  • Controlled drug release
  • Handling and processing of highly potent API's in a glovebox
A small footprint reduces clean room volumes, and lower ingredient consumption reduces handling and operator exposure.

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Frequently asked questions (FAQs)

Citations & References