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Glycine ethyl ester hydrochloride, 99%, Thermo Scientific Chemicals
Catalog number: A10315.22
100 g, Each
Thermo Scientific Chemicals
Glycine ethyl ester hydrochloride, 99%, Thermo Scientific Chemicals
Catalog number: A10315.22
100 g, Each
Quantity
Catalog number: A10315.22
also known as A10315-22
Price (USD)
Price: 28.10
Online price: 23.65
Your price:
Quantity
-
Chemical Identifiers
CAS
623-33-6
IUPAC Name
2-ethoxy-2-oxoethan-1-aminium chloride
Molecular Formula
C4H10ClNO2
InChI Key
TXTWXQXDMWILOF-UHFFFAOYSA-N
SMILES
[Cl-].CCOC(=O)C[NH3+]
Specifications
Specification SheetForm
Crystals or powder or crystalline powder
Identification (FTIR)
Conforms
Melting Point (clear melt)
142.0-149.0°C
Appearance (Color)
White
Assay (Titration ex Chloride)
≥98.5 to ≤101.5%
Description
Glycine ethyl ester (GEE) is used in conjunction with N-(3-Dimethylaminopropyl)-N?-ethylcarbodiimide (EDC) for carboxyl-foot printing studies of proteins. The GEE/EDC protocol effects specific derivatization of glutamate and aspartate carboxyl side chains on intact proteins. This reaction is readily done under aqueous conditions at physiological pH. It is mainly used as a pharmaceutical raw material. Glycine ethyl ester hydrochloride is an important intermediate for preparing chrysanthemic acid or two chlorine chrysanthemic acid and is mainly used in the synthesis of anti-inflammatory drugs, but also can be used for the synthesis of four imidazole acetic acid.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Glycine ethyl ester (GEE) is used in conjunction with N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide (EDC) for carboxyl-foot printing studies of proteins. The GEE/EDC protocol effects specific derivatization of glutamate and aspartate carboxyl side chains on intact proteins. This reaction is readily done under aqueous conditions at physiological pH. It is mainly used as a pharmaceutical raw material. Glycine ethyl ester hydrochloride is an important intermediate for preparing chrysanthemic acid or two chlorine chrysanthemic acid and is mainly used in the synthesis of anti-inflammatory drugs, but also can be used for the synthesis of four imidazole acetic acid.
Solubility
Soluble in water (>1000 mg/ml at 20°C), ethanol, DMSO, and methanol.
Notes
Hygroscopic. Store away from oxidizing agents and water/moisture. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas. Protect from humidity.
Glycine ethyl ester (GEE) is used in conjunction with N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide (EDC) for carboxyl-foot printing studies of proteins. The GEE/EDC protocol effects specific derivatization of glutamate and aspartate carboxyl side chains on intact proteins. This reaction is readily done under aqueous conditions at physiological pH. It is mainly used as a pharmaceutical raw material. Glycine ethyl ester hydrochloride is an important intermediate for preparing chrysanthemic acid or two chlorine chrysanthemic acid and is mainly used in the synthesis of anti-inflammatory drugs, but also can be used for the synthesis of four imidazole acetic acid.
Solubility
Soluble in water (>1000 mg/ml at 20°C), ethanol, DMSO, and methanol.
Notes
Hygroscopic. Store away from oxidizing agents and water/moisture. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Store under inert gas. Protect from humidity.
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