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Thermo Scientific Chemicals
Iodomethane, 99%, stab. with copper
CAS: 74-88-4 | CH3I | 141.94 g/mol
化学物質識別子
CAS74-88-4
IUPAC Nameiodomethane
Molecular FormulaCH3I
InChI KeyINQOMBQAUSQDDS-UHFFFAOYSA-N
SMILESCI
さらに表示
仕様
スペックシート
スペックシートAssay from Suppliers CofA≥98.5% (U.S. specification)
Identification (FTIR)Conforms (non-U.S. specification)
Refractive Index1.5280-1.5330 @ 20°C (non-U.S. specification)
Appearance (Color)Clear colorless to yellow to orange or pale pink
CommentSpecification differs for U.S. and non-U.S. material where indicated
さらに表示
Iodomethane is a methylating agent used for alkylating carbon, oxygen, sulfur, nitrogen and phosphorus nucleophiles. For example, phenol reacts with methyl iodide to give anisole. In the Monsanto process, the insitu formed iodomethane reacts with carbon monoxide in the presence of a rhodium complex to give acetyl iodide, which on hydrolysis yields acetic acid. It reacts with magnesium to form the Grignard reagent, methylmagnesium iodide used in organic synthesis. It finds applications as an intermediate in the manufacture of pharmaceuticals and in phase transfer catalysts.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Iodomethane is a methylating agent used for alkylating carbon, oxygen, sulfur, nitrogen and phosphorus nucleophiles. For example, phenol reacts with methyl iodide to give anisole. In the Monsanto process, the insitu formed iodomethane reacts with carbon monoxide in the presence of a rhodium complex to give acetyl iodide, which on hydrolysis yields acetic acid. It reacts with magnesium to form the Grignard reagent, methylmagnesium iodide used in organic synthesis. It finds applications as an intermediate in the manufacture of pharmaceuticals and in phase transfer catalysts.
Solubility
Miscible with water.
Notes
Light and moisture sensitive. Store in cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, strong bases and oxygen.
Iodomethane is a methylating agent used for alkylating carbon, oxygen, sulfur, nitrogen and phosphorus nucleophiles. For example, phenol reacts with methyl iodide to give anisole. In the Monsanto process, the insitu formed iodomethane reacts with carbon monoxide in the presence of a rhodium complex to give acetyl iodide, which on hydrolysis yields acetic acid. It reacts with magnesium to form the Grignard reagent, methylmagnesium iodide used in organic synthesis. It finds applications as an intermediate in the manufacture of pharmaceuticals and in phase transfer catalysts.
Solubility
Miscible with water.
Notes
Light and moisture sensitive. Store in cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, strong bases and oxygen.
RUO – Research Use Only
General References:
- Erk, B.; Boll, R., Trippel, S.; Anielski, D.; Foucar, L.; Rudek, B.; Rudenko, A. Imaging charge transfer in iodomethane upon x-ray photoabsorption. Science 2014, 345 (6194), 288-291.
- Dong, Y.; Brooks, J. D.; Chen, T. L.; Mullins, D. R.; Cox, D. F. Reactions of methyl groups on a non-reducible metal oxide: The reaction of iodomethane on stoichiometric alpha-Cr 2 O 3 (0001). Surf. Sci. 2015, 641, 148-153.