(+/-)-Camphor-10-sulfonic acid, 98%

Name: (+/-)-Camphor-10-sulfonic acid, 98%
SKU: A12620.22

CAS: 5872-08-2 | C10H16O4S | 232.29 g/mol

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数量:

100 g

500 g

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製品番号（カタログ番号） A12620.22

または、製品番号A12620-22

価格（JPY）

数量:

100 g

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化学物質識別子

CAS5872-08-2

IUPAC Name{7,7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl}methanesulfonic acid

Molecular FormulaC10H16O4S

InChI KeyMIOPJNTWMNEORI-UHFFFAOYNA-N

SMILESCC1(C)C2CCC1(CS(O)(=O)=O)C(=O)C2

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仕様

スペックシート

FormCrystals or powder or crystalline powder or lumps

Water Content (Karl Fischer Titration)≤1.5%

Appearance (Color)White to cream

Assay (Aqueous acid-base Titration)≥97.5 to ≤102.5%

(+)-Camphor-10-sulfonic acid is used as a resolving agent for chiral amines and other cations. It is involved in the preparation of active pharmaceutical ingredient such as trimetaphan camsilate, which is used to reduce bleeding during neurosurgery. Further, it is involved in the transglucosidation of methyl and ethyl D-glucopyranosides by alcoholysis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(+)-Camphor-10-sulfonic acid is used as a resolving agent for chiral amines and other cations. It is involved in the preparation of active pharmaceutical ingredient such as trimetaphan camsilate, which is used to reduce bleeding during neurosurgery. Further, it is involved in the transglucosidation of methyl and ethyl D-glucopyranosides by alcoholysis.

Solubility
Soluble in water.

Notes
Hygroscopic. Incompatible with strong oxidizing agents and strong bases.

RUO – Research Use Only

General References:

Useful acid catalyst, giving high yields in the formation of THP ethers from alcohols; see, e.g.: J. Chem. Soc., Chem. Commun., 413 (1986); Org. Synth., 76, 178 (1998). Catalyst for cycloprotection of 1,2-diols with 1,2-Cyclohexanedione, A14401: Synlett, 793 (1996); Org. Synth., 75, 170 (1997). Preferred catalyst for the intramolecular cyclization of hydroxy epoxides to tetrahydrofurans or tetrahydropyrans: J. Am. Chem. Soc., 111, 5330 (1989).
Chandam, D. R.; Mulik, A. G.; Patil, P. P.; Jagdale, S. D.; Patil, D. R.; Deshmukh, M. B. (±)-Camphor-10-sulfonic acid catalyzed atom efficient and green synthesis of triazolo[1,2-a]indazole-triones and spiro triazolo[1,2-a]indazole-tetraones. Res. Chem. Intermed. 2015, 41 (2), 761-771.
Shelke, A. M.; Suryavanshi, G. An efficient organocatalytic route for asymmetric total synthesis of Stagonolide F. Tetrahedron Lett. 2015, 56 (45), 6207-6209.