Thermo Scientific Chemicals

Diphenyl phosphorochloridate, 97%, Thermo Scientific Chemicals

Catalog number: A13546.18
50 g, Each
Thermo Scientific Chemicals

Diphenyl phosphorochloridate, 97%, Thermo Scientific Chemicals

Catalog number: A13546.18
50 g, Each
Quantity
Catalog number: A13546.18
also known as A13546-18
Price (USD)
Price: 34.80
Online price: 29.65
Your price:
Quantity
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Chemical Identifiers

CAS
2524-64-3
IUPAC Name
diphenyl phosphorochloridate
Molecular Formula
C12H10ClO3P
InChI Key
BHIIGRBMZRSDRI-UHFFFAOYSA-N
SMILES
ClP(=O)(OC1=CC=CC=C1)OC1=CC=CC=C1
Refractive Index
1.5470-1.5520 @ 20?C
Appearance (Color)
Clear colorless
Form
Liquid
Assay (GC)
≥96.0%

Description

Diphenyl phosphorochloridate is used to prepare cyclohexyl-amidophosphoric acid diphenyl ester by reacting with cyclohexylamine. It is also used in the synthesis of alfa-substituted beta-lactams, anhydrides, esters and thioesters. It is also employed in the conversion of aldoximes to nitriles. Further, it is used in the preparation and reaction of enol phosphates, guanosine-adenosine-5',5'-triphosphate, guanosine-cytidine-5',5'-triphosphate, guanosine-uridine-5',5'-triphosphate, diguanosine-5',5'-diphosphate and diguanosine-5',5'-triphosphate. In addition to this, it serves as a phosphorylating agent for the preparation of 2-deoxy-D-galactose-3 and -6 phosphoric acids.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Diphenyl phosphorochloridate is used to prepare cyclohexyl-amidophosphoric acid diphenyl ester by reacting with cyclohexylamine. It is also used in the synthesis of alfa-substituted beta-lactams, anhydrides, esters and thioesters. It is also employed in the conversion of aldoximes to nitriles. Further, it is used in the preparation and reaction of enol phosphates, guanosine-adenosine-5′,5′-triphosphate, guanosine-cytidine-5′,5′-triphosphate, guanosine-uridine-5′,5′-triphosphate, diguanosine-5′,5′-diphosphate and diguanosine-5′,5′-triphosphate. In addition to this, it serves as a phosphorylating agent for the preparation of 2-deoxy-D-galactose-3 and -6 phosphoric acids.

Solubility
Immiscible with water.

Notes
Moisture sensitive. Incompatible with strong bases and strong oxidizing agents.
RUO – Research Use Only

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