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Thermo Scientific Chemicals
7-Amino-4-(trifluoromethyl)coumarin, 97%
CAS: 53518-15-3 | C10H6F3NO2 | 229.158 g/mol
化学物質識別子
CAS53518-15-3
IUPAC Name7-amino-4-(trifluoromethyl)-2H-chromen-2-one
Molecular FormulaC10H6F3NO2
InChI KeyJBNOVHJXQSHGRL-UHFFFAOYSA-N
SMILESNC1=CC=C2C(OC(=O)C=C2C(F)(F)F)=C1
さらに表示
仕様
スペックシート
スペックシートAppearance (Color)Yellow
FormCrystals or powder or crystalline powder
Assay (HPLC)≥96.0%
Identification (FTIR)Conforms
Melting Point (clear melt)218.0-227.0°C
7-Amino-4-(trifluoromethyl)coumarin is used in the synthesis of substrates for the fluorometric assay of proteolytic enzymes in biological fluids. It is suitable as laser dye.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
7-Amino-4-(trifluoromethyl)coumarin is used in the synthesis of substrates for the fluorometric assay of proteolytic enzymes in biological fluids. It is suitable as laser dye.
Solubility
Soluble in dimethyl sulfoxide (25 mg/ml), dimethyl formamide (25 mg/ml), and methanol (25 mg/ml). Insoluble in water.
Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.
7-Amino-4-(trifluoromethyl)coumarin is used in the synthesis of substrates for the fluorometric assay of proteolytic enzymes in biological fluids. It is suitable as laser dye.
Solubility
Soluble in dimethyl sulfoxide (25 mg/ml), dimethyl formamide (25 mg/ml), and methanol (25 mg/ml). Insoluble in water.
Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- Eugene R. Bissell.; Alexander R. Mitchell.; Robert E. Smith. Synthesis and chemistry of 7-amino-4-(trifluoromethyl)coumarin and its amino acid and peptide derivatives. J. Org. Chem. 1980, 45 (12), 2283-2287.
- Chen-Shane Chu.; Yu-Lung Lo. Ratiometric fiber-optic oxygen sensors based on sol-gel matrix doped with metalloporphyrin and 7-amino-4-trifluoromethyl coumarin. Sensors and Actuators B: Chemical. 2008, 134 (2), 711-717.
- Used in synthesis of substrates for fluorometric assay of proteolytic enzymes: Anal. Biochem ., 70, 258 (1976).