Pierce™ Peptide Clean-Up Plate, 96-well

Thermo Scientific™ Pierce™ Peptide Clean-Up Plate products are sorbent-based 96-well plates designed for parallel peptide desalting, clean-up, concentration, and fractionation prior to liquid chromatography-mass spectrometry (LC-MS) and other mass spectrometry (MS) workflows. These plates help remove salts, detergents, buffers, denaturants, chaotropes, and other chemistry-compatible contaminants that can interfere with downstream analysis. The plate portfolio includes multiple peptide clean-up chemistries, including octadecyl silica (C18), strong anion exchange (SAX), mixed-mode cation exchange (MCX), styrene divinylbenzene reversed-phase sulfonate (SDB-RPS), and styrene divinylbenzene crosslinked (SDB-XC), for high-throughput desalting, clean-up, concentration, and fractionation workflows.

Thermo Scientific™ Pierce™ Peptide Clean-Up Plate products use reversed-phase, ion-exchange, or mixed-mode retention to support a range of peptide sample-preparation strategies. The 96-well plate format can be used in centrifugation-based or automation-compatible workflows where appropriate for the selected chemistry and protocol.

Features of Thermo Scientific™ Pierce™ Peptide Clean-Up Plate, 96 well

• High-throughput - process up to 96 peptide samples in a plate-based format
• Flexible - choose from multiple chemistries to support plate-based peptide clean-up, desalting, concentration, and fractionation workflows
• Efficient - help remove LC-MS-incompatible contaminants and prepare peptide samples in MS-compatible solutions for downstream analysis
• Automation-compatible - support automated sample-preparation workflows where appropriate for the selected chemistry and protocol

Applications

• High-throughput peptide desalting prior to liquid chromatography-mass spectrometry (LC-MS) analysis
• Plate-based clean-up following enzymatic protein digestion workflows
• Removal of chemistry-compatible salts, buffers, detergents, denaturants, chaotropes, lipids, and other liquid chromatography-mass spectrometry (LC-MS) interferences
• Plate-based peptide concentration and mass spectrometry sample preparation
• Peptide fractionation to reduce sample complexity and support deeper proteome analysis