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Thermo Scientific Chemicals
alpha-Toluenesulfonyl fluoride, 99%
CAS: 329-98-6 | C7H7FO2S | 174.189 g/mol
化学物質識別子
CAS329-98-6
IUPAC Namephenylmethanesulfonyl fluoride
Molecular FormulaC7H7FO2S
InChI KeyYBYRMVIVWMBXKQ-UHFFFAOYSA-N
SMILESFS(=O)(=O)CC1=CC=CC=C1
さらに表示
仕様
スペックシート
スペックシートAppearance (Color)White
FormCrystals or powder or crystalline powder
Assay (GC)≥98.5%
Identification (FTIR)Conforms
Melting Point91-96?C
α-Toluenesulfonyl fluoride (PMSF) is used in the preparation of cell lysates to inhibit protein digestion. It is a widely used fatty acid amid hydrolase (FAAH) inhibitor for pretreatment of brain membrane preparations when testing CB1 receptor activity.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
α-Toluenesulfonyl fluoride (PMSF) is used in the preparation of cell lysates to inhibit protein digestion. It is a widely used fatty acid amid hydrolase (FAAH) inhibitor for pretreatment of brain membrane preparations when testing CB1 receptor activity.
Solubility
Soluble in ether, benzene, anhydrous ethanol, methanol, 2- propane. Hydrolyses in water.
Notes
Moisture sensitive. Store away from strong oxidizing agents, amines, bases, water/ moisture. Store at 4°C
α-Toluenesulfonyl fluoride (PMSF) is used in the preparation of cell lysates to inhibit protein digestion. It is a widely used fatty acid amid hydrolase (FAAH) inhibitor for pretreatment of brain membrane preparations when testing CB1 receptor activity.
Solubility
Soluble in ether, benzene, anhydrous ethanol, methanol, 2- propane. Hydrolyses in water.
Notes
Moisture sensitive. Store away from strong oxidizing agents, amines, bases, water/ moisture. Store at 4°C
RUO – Research Use Only
General References:
- C Pinsky; A K Dua; F S LaBella. Phenylmethylsulfonyl fluoride (PMSF) given systemically produces naloxone-reversible analgesia and potentiates effects of beta-endorphin given centrally. Life Sciences. 1982, 31 (12-13), 1193-1196.
- G T James.Inactivation of the protease inhibitor phenylmethylsulfonyl fluoride in buffers. Analytical Biochemistry. 1978, 86 (2), 574-579.