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Thermo Scientific Chemicals
Congo Red, indicator grade
CAS: 573-58-0 | C32H22N6Na2O6S2 | 696.664 g/mol
化学物質識別子
CAS573-58-0
IUPAC Namedisodium 4-amino-3-(2-{4'-[2-(1-amino-4-sulfonatonaphthalen-2-yl)diazen-1-yl]-[1,1'-biphenyl]-4-yl}diazen-1-yl)naphthalene-1-sulfonate
Molecular FormulaC32H22N6Na2O6S2
InChI KeyIQFVPQOLBLOTPF-UHFFFAOYSA-L
SMILES[Na+].[Na+].NC1=C2C=CC=CC2=C(C=C1N=NC1=CC=C(C=C1)C1=CC=C(C=C1)N=NC1=CC(=C2C=CC=CC2=C1N)S([O-])(=O)=O)S([O-])(=O)=O
さらに表示
仕様
スペックシート
スペックシートFormPowder
Specific Absorbance (E 1%/1cm)>500 @ lambda-max (pH 7)
Loss on Drying≤5.0%
Solution Test0.1% in water: clear
lambda-max (UV-Vis)490-500nm @ pH 7
さらに表示
Congo red is useful for staining and visual detection of amyloid deposits. It inhibits the accumulation of the scrapie-associated, protease-resistant isoform of protein PrP without affecting the metabolism of the normal isoform.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Congo red is useful for staining and visual detection of amyloid deposits. It inhibits the accumulation of the scrapie-associated, protease-resistant isoform of protein PrP without affecting the metabolism of the normal isoform.
Solubility
Soluble in water 25 g/L.
Notes
Store away from oxidizing agents, acids, reducing agents.
Congo red is useful for staining and visual detection of amyloid deposits. It inhibits the accumulation of the scrapie-associated, protease-resistant isoform of protein PrP without affecting the metabolism of the normal isoform.
Solubility
Soluble in water 25 g/L.
Notes
Store away from oxidizing agents, acids, reducing agents.
RUO – Research Use Only
General References:
- Young Hye Kim; Se Hoon Choi; Carla D'Avanzo; Matthias Hebisch; Christopher Sliwinski; Enjana Bylykbashi; Kevin J Washicosky; Justin B Klee; Oliver Brüstle; Rudolph E Tanzi; Doo Yeon Kim. A 3D human neural cell culture system for modeling Alzheimer's disease. Nature Protocols. 2015, 10 (7), 985-1006.
- D P Penney; J M Powers; M Frank; C Willis; C Churukian. Analysis and testing of biological stains--the Biological Stain Commission Procedures. Biotechnic and Histochemistry. 2002, 77 (5-6), 237-275.