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Thermo Scientific Chemicals
(Trifluoromethyl)trimethylsilane, 0.5M soln. in THF
CAS: 81290-20-2 | C5H11F3Si | 156.22 g/mol
化学物質識別子
CAS81290-20-2
IUPAC Nametert-butyl(trifluoromethyl)silane
Molecular FormulaC5H11F3Si
InChI KeyMTYSDPUZDZURPP-UHFFFAOYSA-N
SMILESCC(C)(C)[SiH2]C(F)(F)F
さらに表示
スペックシートThis Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
A reagent used in nucleophilic addition of the trifluoromethyl group to aldehydes and ketones.
Solubility
Hydrolyzes in water.
Notes
Moisture Sensitive. Store away from oxidizing agents, water/ moisture.
A reagent used in nucleophilic addition of the trifluoromethyl group to aldehydes and ketones.
Solubility
Hydrolyzes in water.
Notes
Moisture Sensitive. Store away from oxidizing agents, water/ moisture.
RUO – Research Use Only
General References:
- G K Surya Prakash; Chiradeep Panja; Habiba Vaghoo; Vijayalakshmi Surampudi; Roman Kultyshev; Mihirbaran Mandal; Golam Rasul; Thomas Mathew; George A Olah. Facile synthesis of TMS-protected trifluoromethylated alcohols using trifluoromethyltrimethylsilane (TMSCF3) and various nucleophilic catalysts in DMF. Journal of Organic Chemistry. 2006, 71 (18), 6806-6813.
- Rajendra P. Singh; Ganfeng Cao; Robert L. Kirchmeier and Jean'ne M. Shreeve. Cesium Fluoride Catalyzed Trifluoromethylation of Esters, Aldehydes, and Ketones with (Trifluoromethyl)trimethylsilane. J. Org. Chem. 1999, 64 (8), 2873-2876.