Quinuclidine acts as a catalyst, a chemical building block and is used in organic synthesis. It is employed to prepare quinine and alkaloids. It finds application as a ligand, which is useful in the studies of OsO
4-catalyzed dihydroxylation of olefins. It plays an important role in the formation of onium salts used testing of PAC-antagonist activity.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Quinuclidine acts as a catalyst, a chemical building block and is used in organic synthesis. It is employed to prepare quinine and alkaloids. It finds application as a ligand, which is useful in the studies of OsO4-catalyzed dihydroxylation of olefins. It plays an important role in the formation of onium salts used testing of PAC-antagonist activity.
Solubility
Soluble in alcohol, diethyl ether, water and organic solvents.
Notes
Air sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents and chloroformates.
RUO – Research Use Only
General References:
- Chan, F. Y.; Sun, N.; Leung, Y. C.; Wong, K. Y. Antimicrobial activity of a quinuclidine-based FtsZ inhibitor and its synergistic potential with beta-lactam antibiotics. J. Antibiot. 2015, 68 (4), 253-258.
- Reddi, Y.; Sunoj, R. B. Asymmetric Dual-Catalytic Cascade by Chiral N-Heterocyclic Carbene and Quinuclidine: Mechanism and Origin of Enantioselectivity in Benzofuranone Formation. ACS Catal. 2015, 5 (3), 1596-1603.