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Thermo Scientific Chemicals
1-Cyano-4-(dimethylamino)pyridinium tetrafluoroborate, 98%
CAS: 59016-56-7 | C8H10BF4N3 | 234.99 g/mol
化学物質識別子
CAS59016-56-7
IUPAC Name1-cyano-4-(dimethylamino)pyridin-1-ium; tetrafluoroboranuide
Molecular FormulaC8H10BF4N3
InChI KeyMBLVMDCQDCVKNE-UHFFFAOYSA-N
SMILESF[B-](F)(F)F.CN(C)C1=CC=[N+](C=C1)C#N
さらに表示
スペックシート1-Cyano-4-(dimethylamino)pyridinium tetrafluoroborate is a cyanylation reagent for protein sulfhydryl groups and used to prepare protein-polysaccharide conjugates. It is employed as an activating agent for polysaccharide resins and conjugation of lipopolysaccharides while retaining endotoxic activity.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
1-Cyano-4-(dimethylamino)pyridinium tetrafluoroborate is a cyanylation reagent for protein sulfhydryl groups and used to prepare protein-polysaccharide conjugates. It is employed as an activating agent for polysaccharide resins and conjugation of lipopolysaccharides while retaining endotoxic activity.
Solubility
Soluble in water, and acetonitrile.
Notes
Store at room temperature. Keep away from oxidizing agents and heats.
1-Cyano-4-(dimethylamino)pyridinium tetrafluoroborate is a cyanylation reagent for protein sulfhydryl groups and used to prepare protein-polysaccharide conjugates. It is employed as an activating agent for polysaccharide resins and conjugation of lipopolysaccharides while retaining endotoxic activity.
Solubility
Soluble in water, and acetonitrile.
Notes
Store at room temperature. Keep away from oxidizing agents and heats.
RUO – Research Use Only
General References:
- Joachim Kohn.; Meir Wilchek. 1-Cyano-4-dimethylamino pyridinium tetrafluoroborate as a cyanylating agent for the covalent attachment of ligand to polysaccharide resins. FEBS Lett. 1983, 154 (1), 209-210.
- Andrew Lees.; Brett L. Nelson.; James J. Mond. Activation of soluble polysaccharides with 1-cyano-4-dimethylaminopyridinium tetrafluoroborate for use in protein—polysaccharide conjugate vaccines and immunological reagents. Vaccine. 1996, 14 (3),190-198.