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Thermo Scientific Chemicals
beta-Nicotinamide adenine dinucleotide reduced disodium salt trihydrate, 98%
CAS: 497934-76-6 | C21H27N7Na2O14P2 3H20 | 709.41 g/mol
化学物質識別子
CAS497934-76-6
IUPAC Namedisodium trihydrate [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl ({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)phosphonate
Molecular FormulaC21H33N7Na2O17P2
InChI KeyNKGIRZCFNXSJBB-ZVYMQMITSA-L
SMILESO.O.O.[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
さらに表示
仕様
スペックシート
スペックシートAppearance (Color)White to cream or pale yellow
FormPowder or crystalline powder
Assay≥97.5%
Assay (unspecified)≥97.5%
Water Content≤7.5%
β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases). As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases). As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.
Solubility
It is soluble in water.
Notes
Store with desiccant. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature -20°C Light sensitive. Hygroscopic.
β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases). As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.
Solubility
It is soluble in water.
Notes
Store with desiccant. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature -20°C Light sensitive. Hygroscopic.
RUO – Research Use Only
General References:
- Richard P. Ebstein et. al. Are retinoids potential therapeutic agents in disorders of social cognition including autism?. FEBS Letters.2011, 585, (11), 1529-1536.
- Xiaoling Li and Nevzat Kazgan. Mammalian sirtuins and energy metabolism. International Journal of Biological Sciences.2011, 7, (5), 575-587.