Spectinomycin dihydrochloride pentahydrate, Cell Culture Grade
Spectinomycin dihydrochloride pentahydrate, Cell Culture Grade
Spectinomycin dihydrochloride pentahydrate, Cell Culture Grade
Thermo Scientific Chemicals

Spectinomycin dihydrochloride pentahydrate, Cell Culture Grade

Spectinomycin dihydrochloride pentahydrate, CAS # 22189-32-8, is the hydrochloride salt form of spectinomycin, an aminocyclitol compound showing antibacterial and antimicrobial activities. | CAS: 22189-32-8 | C14H36Cl2N2O12 | 495.34 g/mol
製品番号(カタログ番号) J61820.14
または、製品番号J61820-14
価格(JPY)
-
数量:
25 g
一括またはカスタム形式をリクエストする
化学物質識別子
CAS22189-32-8
IUPAC Namedihydrogen (1R,3S,5R,8R,10R,11S,12S,13R,14S)-8,12,14-trihydroxy-5-methyl-11,13-bis(methylamino)-2,4,9-trioxatricyclo[8.4.0.0³,⁸]tetradecan-7-one pentahydrate dichloride
Molecular FormulaC14H36Cl2N2O12
InChI KeyDCHJOVNPPSBWHK-UXXUFHFZSA-N
SMILES[H+].[H+].O.O.O.O.O.[Cl-].[Cl-].CN[C@@H]1[C@H](O)[C@H](NC)[C@H]2O[C@]3(O)[C@@H](O[C@H](C)CC3=O)O[C@@H]2[C@H]1O
さらに表示
pH3.5-6.0
FormSlightly hygroscopic powder
Appearance (Color)White to cream
Potency≥ 603 IU/mg
Water Content (Karl Fischer Titration)16.0-20.0%
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Suitable for battery materials development.

General Description

  • Spectinomycin dihydrochloride pentahydrate is derived from Streptomyces spectabilis and presents antibacterial and antimicrobial activities
  • Spectinomycin hydrochloride is a compound that inhibits the 30S ribosomal subunit of bacteria and interrupts protein synthesis and peptide elongation, leading to bacterial cell death

Application

  • Spectinomycin dihydrochloride pentahydrate is a compound that is active against gram-negative bacteria
  • In the laboratory, this compound is used in cell culture applications
  • It prevents contamination and can be used to select for resistant bacteria and plant cells containing the marker gene Spcr
  • It has been used to study respiratory tract infections caused by Pasteurella multocida and Mannheimia haemolytica
  • In genetic approaches, this compound can be used to amplify the plasmid copy number
RUO – Research Use Only

General References:

  1. Korte, H. L.; Saini, A.; Trotter, V. V.; Butland, G. P.; Arkin, A. P.; Wall, J. D. Independence of nitrate and nitrite inhibition of Desulfovibrio vulgaris Hildenborough and use of nitrite as a substrate for growth. Environ. Sci. Technol. 2015, 49 (2), 924-931.
  2. Pernil, R.; Picossi, S.; Herrero, A.; Flores, E.; Mariscal, V. Amino Acid Transporters and Release of Hydrophobic Amino Acids in the Heterocyst-Forming Cyanobacterium Anabaena sp. Strain PCC 7120. Life 2015, 5 (2), 1282-1300.