General Description

• Spectinomycin dihydrochloride pentahydrate is derived from Streptomyces spectabilis and presents antibacterial and antimicrobial activities
• Spectinomycin hydrochloride is a compound that inhibits the 30S ribosomal subunit of bacteria and interrupts protein synthesis and peptide elongation, leading to bacterial cell death

Application

• Spectinomycin dihydrochloride pentahydrate is a compound that is active against gram-negative bacteria
• In the laboratory, this compound is used in cell culture applications
• It prevents contamination and can be used to select for resistant bacteria and plant cells containing the marker gene Spcr
• It has been used to study respiratory tract infections caused by Pasteurella multocida and Mannheimia haemolytica
• In genetic approaches, this compound can be used to amplify the plasmid copy number