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Thiazolyl Blue tetrazolium bromide, 98%
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Catalog number L11939.06
also known as L11939-06
Price (USD)/ Each
189.65
Online exclusive
210.00 Save 20.35 (10%)
-
Quantity:
5 g
Price (USD)/ Each
189.65
Online exclusive
210.00 Save 20.35 (10%)
Thiazolyl Blue tetrazolium bromide, 98%
Catalog numberL11939.06
Price (USD)/ Each
189.65
Online exclusive
210.00 Save 20.35 (10%)
-
Chemical Identifiers
IUPAC Name2-(4,5-dimethyl-1,3-thiazol-2-yl)-3,5-diphenyl-3H-1,2λ⁵,3,4-tetrazol-2-ylium bromide
Molecular FormulaC18H16BrN5S
InChI KeyAZKSAVLVSZKNRD-UHFFFAOYSA-M
SMILES[Br-].CC1=C(C)N=C(S1)[N+]1=NC(=NN1C1=CC=CC=C1)C1=CC=CC=C1
Molecular Weight (g/mol)414.33
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Specifications
Specification Sheet
Specification SheetFormCrystals or powder or crystalline powder
Identification (FTIR)Conforms
Assay (Argentometric Titration)≥97.5 to ≤102.5%
Appearance (Color)White to yellow
Used in measurement of cell proliferation. Produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells.Thiazolyl Blue tetrazolium bromide is a dye used in measurement of cell proliferation. It is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. As an electron acceptor, it is utilized for studying nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Used in measurement of cell proliferation. Produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells.Thiazolyl Blue tetrazolium bromide is a dye used in measurement of cell proliferation. It is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. As an electron acceptor, it is utilized for studying nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.
Solubility
Soluble in water, ethanol, 2-methoxyethanol and phosphate buffered saline.
Notes
Light, air and moisture sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.
Used in measurement of cell proliferation. Produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells.Thiazolyl Blue tetrazolium bromide is a dye used in measurement of cell proliferation. It is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. As an electron acceptor, it is utilized for studying nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.
Solubility
Soluble in water, ethanol, 2-methoxyethanol and phosphate buffered saline.
Notes
Light, air and moisture sensitive. Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Ma, W.; Xu, A.; Ying, J.; Li, B.; Jin, Y. Biodegradable Core-Shell Copolymer-Phospholipid Nanoparticles for Combination Chemotherapy: An In Vitro Study. J. Biomed. Nanotechnol. 2015, 11 (7), 1193-1200.
- Wei, D.; Chen, T.; Yan, M.; Zhao, W.; Li, F.; Cheng, W.; Yuan, L. Synthesis, characterization, antioxidant activity and neuroprotective effects of selenium polysaccharide from Radix hedysari. Carbohydr. Polym. 2015, 125, 161-168.