Fluorescein-CREBtide Substrate

Catalog number:  PV3508

Related applications:

Protein Assays and Analysis

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Description

A fluorescein-labeled peptide substrate that is based upon the CREB ( cAMP responsive element binding) protein. The peptide substrate is phosphorylated by a wide range of Ser/Thr kinases.

For use in combination with the LanthaScreen® Tb-CREB [pSer133] antibody (PV3542) to evaluate inhibitors in medium to high throughput screening applications.
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Amino Acid Sequence: Fluorescein- KRREILSRRPSYR
Assay Entry: Biochemical terbium phospho-specific activity
Detection Method: Fluorescent
Label or Dye: FITC (Fluorescein)
Shipping Condition: Dry Ice
Substrate: Fluorescein-CREBtide
Substrate Properties: Peptide-Based Substrate
Target Entry: AMPK (A2/B1/G1), STK22D, CAMK2B, CHEK1, MAPKAPK2, PASK, PIM2, PRKCN, PRKD2, PRKG2, RPS6KA5, AMPK (A1/B1/G1), AURKA, CAMK1D, CAMK4, CHEK2, MAPKAPK3, PIM1, PKN1, PRKD1, PRKG1, RPS6KA4, CAMK1
Target Enzyme: Serine⁄Threonine Kinases
Validated Kinases: AMPK, AURKA, CAMK1, CAMKID, CAMK2A, CAMK2B, CAMK4, CHEK1, CHEK2, MAPKAPK2, MAPKAPK3, PASK, PIM1, PIM2, PKN1, PRKACA, PRKD1, PRKD2, PRKG1, PRKG2, RPS6KA4, RPS6KA5, STK22D
Substrate Type: Kinase Substrate
Molecular Weight: 2076 Da

Contents & storage

1 mg/mL Fluorescein-CREBtide substrate in water. Store at -20°C and protect from light.