PIP2:PS Lipid Kinase Substrate

      Catalog number:  PV5100

       Related applications: Pharma & Biopharma | Protein Assays and Analysis | Target & Lead Identification & Validation

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      Description

      Specifically optimized for use with the Class I PI3 kinases (PIK3CA, PIK3CB, PIK3CD, and PIK3CG), this substrate consists of lipid vesicles of a 1:19 molar ratio of phosphoinositol-4,5-bisphosphate (PIP2) with phosphoserine (PS).

      For use with the Adapta™ Universal Kinase Assay (PV5099).
      For Research Use Only. Not for use in diagnostic procedures.

      Specifications

      Detection Method: Fluorescent
      Gene ID: 5290, 5294
      Product Size: 400 nmol
      Substrate: Phosphoinositol-4,5-bisphosphate (PIP2) lipid vesicles with phosphoserine (PS)
      Substrate Properties: Lipid-Based Substrate
      Substrate Type: Kinase Substrate
      Target Enzyme: Lipid Kinases
      Validated Kinases: PIK3CA, PIK3CG, PIK3CB, PIK3CD
      Shipping Condition: Dry Ice

      Contents & storage

      PIP2:PS Lipid Kinase Substrate in 50 mM HEPES pH 7.5, 3 mM MgCl2, and 1 mM EGTA. Store at -20°C.

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