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Highest antigen sequence indentity to the following orthologs: Mouse (91%), Rat (91%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53092. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Involved in the establishment of cell polarity in mammalian epithelial cells. Regulates the morphogenesis of tight junctions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: crumbs 3, cell polarity complex component; crumbs family member 3; Protein crumbs homolog 3; similar to GenBank Accession Number BC018409; transmembrane protein; CRB3; unnamed protein product
Gene Aliases: CRB3; UNQ588/PRO1158
UniProt ID: (Human) Q9BUF7
Entrez Gene ID: (Human) 92359
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